This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2r40

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:19, 21 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2r40.png|left|200px]]
 
-
<!--
+
==Crystal structure of 20E bound EcR/USP==
-
The line below this paragraph, containing "STRUCTURE_2r40", creates the "Structure Box" on the page.
+
<StructureSection load='2r40' size='340' side='right'caption='[[2r40]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2r40]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Heliothis_virescens Heliothis virescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R40 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.402&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=20E:(2BETA,3BETA,5BETA,22R)-2,3,14,20,22,25-HEXAHYDROXYCHOLEST-7-EN-6-ONE'>20E</scene>, <scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
{{STRUCTURE_2r40| PDB=2r40 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r40 OCA], [https://pdbe.org/2r40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r40 RCSB], [https://www.ebi.ac.uk/pdbsum/2r40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r40 ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of 20E bound EcR/USP===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/ECR_HELVI ECR_HELVI] Receptor for ecdysone. Binds to ecdysone response elements (ECRES) (By similarity).
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_17848566}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 17848566 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r4/2r40_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_17848566}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
2R40 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Heliothis_virescens Heliothis virescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R40 OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r40 ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
<ref group="xtra">PMID:17848566</ref><references group="xtra"/>
+
</StructureSection>
[[Category: Heliothis virescens]]
[[Category: Heliothis virescens]]
-
[[Category: Billas, I M.L.]]
+
[[Category: Large Structures]]
-
[[Category: Browning, C.]]
+
[[Category: Billas IML]]
-
[[Category: Moras, D.]]
+
[[Category: Browning C]]
-
[[Category: Anti-parallel alpha-helical sandwich]]
+
[[Category: Moras D]]
-
[[Category: Ecdysone receptor]]
+
-
[[Category: Ecr]]
+
-
[[Category: Gene regulation]]
+
-
[[Category: Nuclear receptor ligand-binding domain]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:52:24 2009''
+

Current revision

Crystal structure of 20E bound EcR/USP

PDB ID 2r40

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2r40"
Personal tools