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1gio

From Proteopedia

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{{Seed}}
 
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[[Image:1gio.png|left|200px]]
 
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==NMR SOLUTION STRUCTURE OF BOVINE ANGIOGENIN, 10 STRUCTURES==
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The line below this paragraph, containing "STRUCTURE_1gio", creates the "Structure Box" on the page.
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<StructureSection load='1gio' size='340' side='right'caption='[[1gio]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1gio]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GIO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gio OCA], [https://pdbe.org/1gio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gio RCSB], [https://www.ebi.ac.uk/pdbsum/1gio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gio ProSAT]</span></td></tr>
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{{STRUCTURE_1gio| PDB=1gio | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ANG1_BOVIN ANG1_BOVIN] May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. Has very low ribonuclease activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gi/1gio_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gio ConSurf].
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<div style="clear:both"></div>
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===NMR SOLUTION STRUCTURE OF BOVINE ANGIOGENIN, 10 STRUCTURES===
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8688423}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8688423 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8688423}}
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==About this Structure==
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1GIO is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GIO OCA].
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==Reference==
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<ref group="xtra">PMID:8688423</ref><references group="xtra"/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Albaret, C.]]
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[[Category: Large Structures]]
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[[Category: Bontems, F.]]
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[[Category: Albaret C]]
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[[Category: Lallemand, J Y.]]
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[[Category: Bontems F]]
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[[Category: Lequin, O.]]
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[[Category: Lallemand JY]]
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[[Category: Spik, G.]]
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[[Category: Lequin O]]
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[[Category: Endoribonuclease]]
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[[Category: Spik G]]
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[[Category: Hydrolase angiogenesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:35:08 2009''
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Current revision

NMR SOLUTION STRUCTURE OF BOVINE ANGIOGENIN, 10 STRUCTURES

PDB ID 1gio

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