1mx3

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{{Seed}}
 
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[[Image:1mx3.png|left|200px]]
 
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==Crystal structure of CtBP dehydrogenase core holo form==
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The line below this paragraph, containing "STRUCTURE_1mx3", creates the "Structure Box" on the page.
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<StructureSection load='1mx3' size='340' side='right'caption='[[1mx3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mx3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MX3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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{{STRUCTURE_1mx3| PDB=1mx3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mx3 OCA], [https://pdbe.org/1mx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mx3 RCSB], [https://www.ebi.ac.uk/pdbsum/1mx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mx3 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of CtBP dehydrogenase core holo form===
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== Function ==
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[https://www.uniprot.org/uniprot/CTBP1_HUMAN CTBP1_HUMAN] Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.<ref>PMID:9858600</ref> <ref>PMID:15542832</ref> <ref>PMID:19103759</ref> <ref>PMID:12419229</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12419229 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mx/1mx3_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12419229}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1MX3 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MX3 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mx3 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:12419229</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Aggarwal, A K.]]
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[[Category: Large Structures]]
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[[Category: Carlson, J E.]]
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[[Category: Aggarwal AK]]
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[[Category: Edwards, T E.]]
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[[Category: Carlson JE]]
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[[Category: Escalante, C R.]]
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[[Category: Edwards TE]]
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[[Category: Kumar, V.]]
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[[Category: Escalante CR]]
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[[Category: Ohgi, K E.]]
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[[Category: Kumar V]]
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[[Category: Rose, D W.]]
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[[Category: Ohgi KE]]
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[[Category: Nuclear protein]]
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[[Category: Rose DW]]
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[[Category: Phosphorylation]]
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[[Category: Transcriptional corepressor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:44:24 2009''
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Current revision

Crystal structure of CtBP dehydrogenase core holo form

PDB ID 1mx3

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