1mdr
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1mdr.png|left|200px]] | ||
- | + | ==THE ROLE OF LYSINE 166 IN THE MECHANISM OF MANDELATE RACEMASE FROM PSEUDOMONAS PUTIDA: MECHANISTIC AND CRYSTALLOGRAPHIC EVIDENCE FOR STEREOSPECIFIC ALKYLATION BY (R)-ALPHA-PHENYLGLYCIDATE== | |
- | + | <StructureSection load='1mdr' size='340' side='right'caption='[[1mdr]], [[Resolution|resolution]] 2.10Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1mdr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MDR FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
- | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APG:ATROLACTIC+ACID+(2-PHENYL-LACTIC+ACID)'>APG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mdr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mdr OCA], [https://pdbe.org/1mdr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mdr RCSB], [https://www.ebi.ac.uk/pdbsum/1mdr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mdr ProSAT]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/MANR_PSEPU MANR_PSEPU] | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/1mdr_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mdr ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Mandelate racemase|Mandelate racemase]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | [[Category: Large Structures]] | |
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- | [[Category: | + | |
[[Category: Pseudomonas putida]] | [[Category: Pseudomonas putida]] | ||
- | [[Category: Fujita | + | [[Category: Fujita S]] |
- | [[Category: Gerlt | + | [[Category: Gerlt JA]] |
- | [[Category: Kenyon | + | [[Category: Kenyon GL]] |
- | [[Category: Koo | + | [[Category: Koo CW]] |
- | [[Category: Kozarich | + | [[Category: Kozarich JW]] |
- | [[Category: Landro | + | [[Category: Landro JA]] |
- | [[Category: Neidhart | + | [[Category: Neidhart DJ]] |
- | [[Category: Petsko | + | [[Category: Petsko GA]] |
- | [[Category: Shah | + | [[Category: Shah VJ]] |
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Current revision
THE ROLE OF LYSINE 166 IN THE MECHANISM OF MANDELATE RACEMASE FROM PSEUDOMONAS PUTIDA: MECHANISTIC AND CRYSTALLOGRAPHIC EVIDENCE FOR STEREOSPECIFIC ALKYLATION BY (R)-ALPHA-PHENYLGLYCIDATE
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Categories: Large Structures | Pseudomonas putida | Fujita S | Gerlt JA | Kenyon GL | Koo CW | Kozarich JW | Landro JA | Neidhart DJ | Petsko GA | Shah VJ