1a8r

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{{Seed}}
 
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[[Image:1a8r.png|left|200px]]
 
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==GTP CYCLOHYDROLASE I (H112S MUTANT) IN COMPLEX WITH GTP==
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The line below this paragraph, containing "STRUCTURE_1a8r", creates the "Structure Box" on the page.
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<StructureSection load='1a8r' size='340' side='right'caption='[[1a8r]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1a8r]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A8R FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
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{{STRUCTURE_1a8r| PDB=1a8r | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a8r OCA], [https://pdbe.org/1a8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a8r RCSB], [https://www.ebi.ac.uk/pdbsum/1a8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a8r ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GCH1_ECOLI GCH1_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a8/1a8r_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a8r ConSurf].
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<div style="clear:both"></div>
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===GTP CYCLOHYDROLASE I (H112S MUTANT) IN COMPLEX WITH GTP===
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==See Also==
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*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12559918}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12559918 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12559918}}
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==About this Structure==
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1A8R is a 15 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A8R OCA].
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==Reference==
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<ref group="xtra">PMID:12559918</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: GTP cyclohydrolase I]]
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[[Category: Large Structures]]
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[[Category: Auerbach, G.]]
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[[Category: Auerbach G]]
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[[Category: Bacher, A.]]
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[[Category: Bacher A]]
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[[Category: Bracher, A.]]
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[[Category: Bracher A]]
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[[Category: Huber, R.]]
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[[Category: Huber R]]
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[[Category: Nar, H.]]
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[[Category: Nar H]]
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[[Category: Gtp]]
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[[Category: Hydrolase]]
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[[Category: Pterine synthesis]]
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[[Category: Purine hydrolysis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:41:28 2009''
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Current revision

GTP CYCLOHYDROLASE I (H112S MUTANT) IN COMPLEX WITH GTP

PDB ID 1a8r

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