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1qa9

From Proteopedia

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{{Seed}}
 
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[[Image:1qa9.png|left|200px]]
 
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<!--
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==Structure of a Heterophilic Adhesion Complex Between the Human CD2 and CD58(LFA-3) Counter-Receptors==
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The line below this paragraph, containing "STRUCTURE_1qa9", creates the "Structure Box" on the page.
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<StructureSection load='1qa9' size='340' side='right'caption='[[1qa9]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qa9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QA9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qa9 OCA], [https://pdbe.org/1qa9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qa9 RCSB], [https://www.ebi.ac.uk/pdbsum/1qa9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qa9 ProSAT]</span></td></tr>
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{{STRUCTURE_1qa9| PDB=1qa9 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CD2_HUMAN CD2_HUMAN] CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qa/1qa9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qa9 ConSurf].
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<div style="clear:both"></div>
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===Structure of a Heterophilic Adhesion Complex Between the Human CD2 and CD58(LFA-3) Counter-Receptors===
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==See Also==
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*[[CD2|CD2]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10380930}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10380930 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_10380930}}
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==About this Structure==
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1QA9 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QA9 OCA].
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==Reference==
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<ref group="xtra">PMID:10380930</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kim, M.]]
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[[Category: Large Structures]]
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[[Category: Liu, J H.]]
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[[Category: Kim M]]
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[[Category: Reinherz, E L.]]
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[[Category: Liu J-H]]
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[[Category: Smolyar, A.]]
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[[Category: Reinherz EL]]
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[[Category: Sun, Z J.]]
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[[Category: Smolyar A]]
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[[Category: Tan, K.]]
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[[Category: Sun ZJ]]
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[[Category: Wagner, G.]]
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[[Category: Tan K]]
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[[Category: Wang, J H.]]
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[[Category: Wagner G]]
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[[Category: Cd2]]
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[[Category: Wang J-H]]
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[[Category: Cd58]]
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[[Category: Cell adhesion]]
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[[Category: Ig-like domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:00:16 2009''
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Current revision

Structure of a Heterophilic Adhesion Complex Between the Human CD2 and CD58(LFA-3) Counter-Receptors

PDB ID 1qa9

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