1ky1

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{{Seed}}
 
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[[Image:1ky1.png|left|200px]]
 
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==METHIONINE CORE MUTANT OF T4 LYSOZYME==
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The line below this paragraph, containing "STRUCTURE_1ky1", creates the "Structure Box" on the page.
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<StructureSection load='1ky1' size='340' side='right'caption='[[1ky1]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ky1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KY1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
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{{STRUCTURE_1ky1| PDB=1ky1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ky1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ky1 OCA], [https://pdbe.org/1ky1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ky1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ky1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ky1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/1ky1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ky1 ConSurf].
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<div style="clear:both"></div>
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===METHIONINE CORE MUTANT OF T4 LYSOZYME===
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==See Also==
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_12646375}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 12646375 is the PubMed ID number.
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</StructureSection>
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[[Category: Escherichia virus T4]]
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{{ABSTRACT_PUBMED_12646375}}
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[[Category: Large Structures]]
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[[Category: Baase WA]]
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==About this Structure==
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[[Category: Busam RD]]
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1KY1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KY1 OCA].
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[[Category: Gassner NC]]
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[[Category: Lindstrom JD]]
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==Reference==
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[[Category: Matthews BW]]
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<ref group="xtra">PMID:12646375</ref><references group="xtra"/>
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[[Category: Mooers BH]]
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[[Category: Enterobacteria phage t4]]
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[[Category: Quillin ML]]
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[[Category: Lysozyme]]
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[[Category: Weaver LH]]
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[[Category: Baase, W A.]]
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[[Category: Busam, R D.]]
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[[Category: Gassner, N C.]]
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[[Category: Lindstrom, J D.]]
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[[Category: Matthews, B W.]]
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[[Category: Mooers, B H.]]
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[[Category: Quillin, M L.]]
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[[Category: Weaver, L H.]]
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[[Category: Methionine core mutant]]
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[[Category: Protein engineering]]
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[[Category: Protein folding]]
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[[Category: T4 lysozyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:47:10 2009''
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Current revision

METHIONINE CORE MUTANT OF T4 LYSOZYME

PDB ID 1ky1

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