2d7h

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{{Seed}}
 
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[[Image:2d7h.png|left|200px]]
 
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==Crystal structure of the ccc complex of the N-terminal domain of PriA==
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The line below this paragraph, containing "STRUCTURE_2d7h", creates the "Structure Box" on the page.
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<StructureSection load='2d7h' size='340' side='right'caption='[[2d7h]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2d7h]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D7H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d7h OCA], [https://pdbe.org/2d7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d7h RCSB], [https://www.ebi.ac.uk/pdbsum/2d7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d7h ProSAT]</span></td></tr>
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{{STRUCTURE_2d7h| PDB=2d7h | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRIA_ECOLI PRIA_ECOLI] Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. Is also involved in initiation of normal DNA replication in various plasmids and phages. Binds to branched DNA structures that resemble D-loops or to the primosome assembly site (PAS). Binds to DNA in two distinct modes, either dependent on or independent of the 3' terminus recognition.<ref>PMID:2825188</ref> <ref>PMID:8366072</ref> <ref>PMID:10356325</ref> <ref>PMID:10956036</ref> <ref>PMID:11929519</ref> <ref>PMID:12622722</ref> <ref>PMID:12917421</ref> <ref>PMID:15576682</ref> <ref>PMID:17483094</ref> <ref>PMID:23264623</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d7/2d7h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d7h ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the ccc complex of the N-terminal domain of PriA===
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==See Also==
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*[[Helicase 3D structures|Helicase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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2D7H is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7H OCA].
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Escherichia coli K-12]]
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<ref group="xtra">PMID:16226927</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Escherichia coli]]
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[[Category: Synthetic construct]]
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[[Category: Kohda, D.]]
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[[Category: Kohda D]]
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[[Category: Maenaka, K.]]
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[[Category: Maenaka K]]
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[[Category: Masai, H.]]
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[[Category: Masai H]]
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[[Category: Ose, T.]]
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[[Category: Ose T]]
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[[Category: Sasaki, K.]]
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[[Category: Sasaki K]]
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[[Category: Protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:02:40 2009''
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Current revision

Crystal structure of the ccc complex of the N-terminal domain of PriA

PDB ID 2d7h

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