1xdp

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{{Seed}}
 
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[[Image:1xdp.png|left|200px]]
 
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==Crystal Structure of the E.coli Polyphosphate Kinase in complex with AMPPNP==
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The line below this paragraph, containing "STRUCTURE_1xdp", creates the "Structure Box" on the page.
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<StructureSection load='1xdp' size='340' side='right'caption='[[1xdp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xdp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XDP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1xdp| PDB=1xdp | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xdp OCA], [https://pdbe.org/1xdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xdp RCSB], [https://www.ebi.ac.uk/pdbsum/1xdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xdp ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of the E.coli Polyphosphate Kinase in complex with AMPPNP===
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== Function ==
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[https://www.uniprot.org/uniprot/PPK1_ECOLI PPK1_ECOLI] Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Can form linear polymers of orthophosphate with chain lengths up to 1000 or more. Can use GTP instead of ATP, but the efficiency of GTP is 5% that of ATP. Also exhibits several other enzymatic activities, which include: ATP synthesis from polyP in the presence of excess ADP, general nucleoside-diphosphate kinase activity, linear guanosine 5'-tetraphosphate (ppppG) synthesis and autophosphorylation.<ref>PMID:10660553</ref> <ref>PMID:8962061</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15947782}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15947782 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xd/1xdp_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15947782}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1XDP is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XDP OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xdp ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:15947782</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Polyphosphate kinase]]
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[[Category: Large Structures]]
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[[Category: Huang, W.]]
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[[Category: Huang W]]
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[[Category: Lee, S S.]]
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[[Category: Lee SS]]
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[[Category: Xu, W.]]
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[[Category: Xu W]]
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[[Category: Zhu, Y.]]
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[[Category: Zhu Y]]
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[[Category: Amppnp]]
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[[Category: E coli polyphosphate kinase]]
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[[Category: Ppk]]
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[[Category: Ppk complex with amppnp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:18:38 2009''
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Current revision

Crystal Structure of the E.coli Polyphosphate Kinase in complex with AMPPNP

PDB ID 1xdp

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