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2riy

From Proteopedia

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{{Seed}}
 
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[[Image:2riy.png|left|200px]]
 
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==B-specific-1,3-galactosyltransferase (GTB)+H-antigen acceptor==
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The line below this paragraph, containing "STRUCTURE_2riy", creates the "Structure Box" on the page.
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<StructureSection load='2riy' size='340' side='right'caption='[[2riy]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2riy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RIY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BHE:OCTYL+2-O-(6-DEOXY-ALPHA-L-GALACTOPYRANOSYL)-BETA-D-GALACTOPYRANOSIDE'>BHE</scene></td></tr>
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{{STRUCTURE_2riy| PDB=2riy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2riy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2riy OCA], [https://pdbe.org/2riy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2riy RCSB], [https://www.ebi.ac.uk/pdbsum/2riy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2riy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/2riy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2riy ConSurf].
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<div style="clear:both"></div>
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===B-specific-1,3-galactosyltransferase (GTB)+H-antigen acceptor===
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==See Also==
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_18192272}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 18192272 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18192272}}
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==Disease==
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Known disease associated with this structure: Blood group, ABO system OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=110300 110300]]
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==About this Structure==
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2RIY is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIY OCA].
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==Reference==
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<ref group="xtra">PMID:18192272</ref><references group="xtra"/>
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[[Category: Fucosylgalactoside 3-alpha-galactosyltransferase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Alfaro, J A.]]
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[[Category: Large Structures]]
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[[Category: Evans, S V.]]
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[[Category: Alfaro JA]]
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[[Category: Blood group antigen]]
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[[Category: Evans SV]]
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[[Category: Glycoprotein]]
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[[Category: Glycosyltransferase]]
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[[Category: Golgi apparatus]]
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[[Category: Gtb abo rossman fold bbbb unliganded]]
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[[Category: Manganese]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Polymorphism]]
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[[Category: Secreted]]
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[[Category: Signal-anchor]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:46:42 2009''
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Current revision

B-specific-1,3-galactosyltransferase (GTB)+H-antigen acceptor

PDB ID 2riy

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