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2idv

From Proteopedia

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{{Seed}}
 
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[[Image:2idv.png|left|200px]]
 
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<!--
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==Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP==
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The line below this paragraph, containing "STRUCTURE_2idv", creates the "Structure Box" on the page.
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<StructureSection load='2idv' size='340' side='right'caption='[[2idv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2idv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IDV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M7G:7N-METHYL-8-HYDROGUANOSINE-5-DIPHOSPHATE'>M7G</scene></td></tr>
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{{STRUCTURE_2idv| PDB=2idv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2idv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2idv OCA], [https://pdbe.org/2idv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2idv RCSB], [https://www.ebi.ac.uk/pdbsum/2idv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2idv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IF4E1_WHEAT IF4E1_WHEAT] Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/id/2idv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2idv ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP===
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==See Also==
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*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17322339}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 17322339 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_17322339}}
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==About this Structure==
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2IDV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IDV OCA].
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==Reference==
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<ref group="xtra">PMID:17322339</ref><references group="xtra"/>
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[[Category: Triticum aestivum]]
[[Category: Triticum aestivum]]
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[[Category: Browning, K S.]]
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[[Category: Browning KS]]
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[[Category: Dhaliwal, S.]]
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[[Category: Dhaliwal S]]
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[[Category: Dutt-Chaudhuri, A.]]
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[[Category: Dutt-Chaudhuri A]]
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[[Category: Hoffman, D W.]]
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[[Category: Hoffman DW]]
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[[Category: Monzingo, A F.]]
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[[Category: Monzingo AF]]
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[[Category: Robertus, J D.]]
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[[Category: Robertus JD]]
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[[Category: Sadow, J.]]
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[[Category: Sadow J]]
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[[Category: Cap]]
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[[Category: Eif4e]]
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[[Category: Eukaryotic initiation factor 4e]]
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[[Category: Methyl-7-gdp]]
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[[Category: Translation regulator]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:18:35 2009''
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Current revision

Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP

PDB ID 2idv

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