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3pbh

From Proteopedia

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{{Seed}}
 
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[[Image:3pbh.png|left|200px]]
 
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<!--
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==REFINED CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN B AT 2.5 ANGSTROM RESOLUTION==
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The line below this paragraph, containing "STRUCTURE_3pbh", creates the "Structure Box" on the page.
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<StructureSection load='3pbh' size='340' side='right'caption='[[3pbh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3pbh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PBH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pbh OCA], [https://pdbe.org/3pbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pbh RCSB], [https://www.ebi.ac.uk/pdbsum/3pbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pbh ProSAT]</span></td></tr>
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{{STRUCTURE_3pbh| PDB=3pbh | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/3pbh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3pbh ConSurf].
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<div style="clear:both"></div>
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===REFINED CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN B AT 2.5 ANGSTROM RESOLUTION===
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==See Also==
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*[[Cathepsin 3D structures|Cathepsin 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8617355}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8617355 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_8617355}}
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==About this Structure==
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3PBH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PBH OCA].
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==Reference==
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<ref group="xtra">PMID:8617355</ref><references group="xtra"/>
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[[Category: Cathepsin B]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kuhelj, R.]]
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[[Category: Large Structures]]
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[[Category: Podobnik, M.]]
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[[Category: Kuhelj R]]
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[[Category: Turk, D.]]
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[[Category: Podobnik M]]
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[[Category: Turk, V.]]
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[[Category: Turk D]]
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[[Category: Cathepsin b]]
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[[Category: Turk V]]
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[[Category: Crystal structure]]
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[[Category: Cysteine protease]]
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[[Category: Papain]]
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[[Category: Proenzyme]]
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[[Category: Thiol protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:21:45 2009''
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Current revision

REFINED CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN B AT 2.5 ANGSTROM RESOLUTION

PDB ID 3pbh

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