1m99

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{{Seed}}
 
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[[Image:1m99.png|left|200px]]
 
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==Crystal structure of the 26 kDa glutathione S-transferase from Schistosoma japonicum complexed with glutathione sulfonic acid==
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The line below this paragraph, containing "STRUCTURE_1m99", creates the "Structure Box" on the page.
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<StructureSection load='1m99' size='340' side='right'caption='[[1m99]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1m99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_japonicum Schistosoma japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M99 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTS:GLUTATHIONE+SULFONIC+ACID'>GTS</scene></td></tr>
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{{STRUCTURE_1m99| PDB=1m99 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m99 OCA], [https://pdbe.org/1m99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m99 RCSB], [https://www.ebi.ac.uk/pdbsum/1m99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m99 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GST26_SCHJA GST26_SCHJA] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m9/1m99_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m99 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the 26 kDa glutathione S-transferase from Schistosoma japonicum complexed with glutathione sulfonic acid===
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==See Also==
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12596270}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12596270 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12596270}}
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==About this Structure==
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1M99 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Schistosoma_japonicum Schistosoma japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M99 OCA].
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==Reference==
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<ref group="xtra">PMID:12596270</ref><references group="xtra"/>
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[[Category: Glutathione transferase]]
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[[Category: Schistosoma japonicum]]
[[Category: Schistosoma japonicum]]
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[[Category: Bruns, C M.]]
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[[Category: Bruns CM]]
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[[Category: Cardoso, R M.F.]]
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[[Category: Cardoso RMF]]
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[[Category: Daniels, D S.]]
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[[Category: Daniels DS]]
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[[Category: Tainer, J A.]]
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[[Category: Tainer JA]]
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[[Category: Antigen]]
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[[Category: Glutathione transferase]]
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[[Category: Multigene family]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:35:42 2009''
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Current revision

Crystal structure of the 26 kDa glutathione S-transferase from Schistosoma japonicum complexed with glutathione sulfonic acid

PDB ID 1m99

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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