1a7v

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{{Seed}}
 
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[[Image:1a7v.png|left|200px]]
 
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==CYTOCHROME C' FROM RHODOPSEUDOMONAS PALUSTRIS==
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The line below this paragraph, containing "STRUCTURE_1a7v", creates the "Structure Box" on the page.
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<StructureSection load='1a7v' size='340' side='right'caption='[[1a7v]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1a7v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A7V FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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{{STRUCTURE_1a7v| PDB=1a7v | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a7v OCA], [https://pdbe.org/1a7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a7v RCSB], [https://www.ebi.ac.uk/pdbsum/1a7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a7v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CYCP_RHOPA CYCP_RHOPA] Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a7/1a7v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a7v ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of an unusual monomeric cytochrome c' from Rhodopseudomonas palustris (RPCP) has been determined at 2.3 A resolution. RPCP has the four-helix (helices A, B, C and D) bundle structure similar to dimeric cytochromes c'. However the amino acid composition of the surface of helices A and B in RPCP is remarkably different from that of the dimeric cytochromes c'. This surface forms the dimer interface in the latter proteins. RPCP has seven charged residues on this surface contrary to the dimeric cytochromes c', which have only two or three charged groups on the corresponding surface. Moreover, hydrophobic residues on this surface of RPCP are two to three times fewer than in dimeric cytochromes c'. As a result of the difference in amino acid composition, the A-B surface of RPCP is rather hydrophilic compared with dimeric cytochromes c'. We thus suggest that RPCP is monomeric in solution because of the hydrophilic nature of the A-B surface. The amino acid composition of the A-B surface is similar to that of Rhodobacter capsulatus cytochrome c' (RCCP), which is an equilibrium admixture of monomer and dimer. The charge distribution of the A-B surface in RCCP, however, is considerably different from that of RPCP. Due to the difference, RCCP can form dimers by both ionic and hydrophobic interactions. These dimers are quite different from those in proteins which form strong dimers such as in Chromatium vinosum, Rhodospirillum rubrum, Rhodospirillum molischianum and Alcaligenes. Cytochrome c' can be classified into two types. Type 1 cytochromes c' have hydrophobic A-B surfaces and they are globular. The A-B surface of type 2 cytochromes c' is hydrophilic and they take a monomeric or flattened dimeric form.
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===CYTOCHROME C' FROM RHODOPSEUDOMONAS PALUSTRIS===
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Basis for monomer stabilization in Rhodopseudomonas palustris cytochrome c' derived from the crystal structure.,Shibata N, Iba S, Misaki S, Meyer TE, Bartsch RG, Cusanovich MA, Morimoto Y, Higuchi Y, Yasuoka N J Mol Biol. 1998 Dec 4;284(3):751-60. PMID:9826513<ref>PMID:9826513</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1a7v" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_9826513}}, adds the Publication Abstract to the page
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*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9826513 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_9826513}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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1A7V is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rhodopseudomonas_palustris Rhodopseudomonas palustris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7V OCA].
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==Reference==
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<ref group="xtra">PMID:9826513</ref><references group="xtra"/>
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[[Category: Rhodopseudomonas palustris]]
[[Category: Rhodopseudomonas palustris]]
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[[Category: Bartsch, R G.]]
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[[Category: Bartsch RG]]
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[[Category: Cusanovich, M A.]]
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[[Category: Cusanovich MA]]
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[[Category: Higuchi, Y.]]
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[[Category: Higuchi Y]]
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[[Category: Iba, S.]]
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[[Category: Iba S]]
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[[Category: Meyer, T E.]]
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[[Category: Meyer TE]]
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[[Category: Misaki, S.]]
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[[Category: Misaki S]]
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[[Category: Shibata, N.]]
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[[Category: Shibata N]]
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[[Category: Yasuoka, N.]]
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[[Category: Yasuoka N]]
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[[Category: Electron transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 10:01:33 2009''
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Current revision

CYTOCHROME C' FROM RHODOPSEUDOMONAS PALUSTRIS

PDB ID 1a7v

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