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2k98

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{{Seed}}
 
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[[Image:2k98.png|left|200px]]
 
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==Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle==
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The line below this paragraph, containing "STRUCTURE_2k98", creates the "Structure Box" on the page.
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<StructureSection load='2k98' size='340' side='right'caption='[[2k98]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2k98]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K98 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k98 OCA], [https://pdbe.org/2k98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k98 RCSB], [https://www.ebi.ac.uk/pdbsum/2k98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k98 ProSAT]</span></td></tr>
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{{STRUCTURE_2k98| PDB=2k98 | SCENE= }}
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Essential understanding: Elucidation of structural requirements and interactions of antimicrobial peptides with lipopolysaccharide (LPS) are essential to understand the mechanism of action of antimicrobial peptides. The highly active antimicrobial peptide MSI-594 (see figure for electrostatic potential surface) acquires a novel helical hairpin structure in complex with LPS. The structure and interactions of MSI-594 with LPS presented here provide important insights into the mechanism of outer membrane permeabilization by antimicrobial peptides.
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===Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle===
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Helical Hairpin Structure of a Potent Antimicrobial Peptide MSI-594 in Lipopolysaccharide Micelles by NMR Spectroscopy.,Bhunia A, Ramamoorthy A, Bhattacharjya S Chemistry. 2009 Jan 29;15(9):2036-2040. PMID:19180607<ref>PMID:19180607</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2k98" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 19180607 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_19180607}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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2K98 is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K98 OCA].
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[[Category: Bhattacharjya S]]
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[[Category: Bhunia A]]
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==Reference==
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[[Category: Ramamoorthy A]]
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<ref group="xtra">PMID:19180607</ref><references group="xtra"/>
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[[Category: Bhattacharjya, S.]]
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[[Category: Bhunia, A.]]
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[[Category: Ramamoorthy, A.]]
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[[Category: Antimicrobial peptide]]
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[[Category: Antimicrobial protein]]
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[[Category: Lp]]
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[[Category: Msi-594]]
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[[Category: Nmr]]
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[[Category: Trnoe]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 25 08:17:05 2009''
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Current revision

Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle

PDB ID 2k98

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