3ga7

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[[Image:3ga7.jpg|left|200px]]
 
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==1.55 Angstrom Crystal Structure of an Acetyl Esterase from Salmonella typhimurium==
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<StructureSection load='3ga7' size='340' side='right'caption='[[3ga7]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ga7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GA7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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{{STRUCTURE_3ga7| PDB=3ga7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ga7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga7 OCA], [https://pdbe.org/3ga7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ga7 RCSB], [https://www.ebi.ac.uk/pdbsum/3ga7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga7 ProSAT], [https://www.topsan.org/Proteins/CSGID/3ga7 TOPSAN]</span></td></tr>
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</table>
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===1.55 Angstrom Crystal Structure of an Acetyl Esterase from Salmonella typhimurium===
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== Function ==
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[https://www.uniprot.org/uniprot/AES_SALTY AES_SALTY] Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity (By similarity).
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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3GA7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA7 OCA].
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Check<jmol>
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[[Category: Salmonella typhimurium]]
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<jmolCheckbox>
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[[Category: Anderson, W F.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3ga7_consurf.spt"</scriptWhenChecked>
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[[Category: Brunzelle, J.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Minasov, G.]]
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</jmolCheckbox>
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[[Category: Onopriyenko, O.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ga7 ConSurf].
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[[Category: Savchenko, A.]]
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<div style="clear:both"></div>
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[[Category: Scott, P.]]
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__TOC__
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[[Category: Skarina, T.]]
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</StructureSection>
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[[Category: Wawrzak, Z.]]
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[[Category: Large Structures]]
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[[Category: Acetyl esterase]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Anderson WF]]
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[[Category: Csgid]]
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[[Category: Brunzelle J]]
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[[Category: Cytoplasm]]
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[[Category: Minasov G]]
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[[Category: Hydrolase]]
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[[Category: Onopriyenko O]]
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[[Category: Idp00896]]
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[[Category: Peterson SN]]
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[[Category: Phosphoserine]]
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[[Category: Savchenko A]]
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[[Category: Serine esterase]]
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[[Category: Skarina T]]
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[[Category: Structural genomic]]
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[[Category: Wawrzak Z]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 25 09:38:55 2009''
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Current revision

1.55 Angstrom Crystal Structure of an Acetyl Esterase from Salmonella typhimurium

PDB ID 3ga7

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