2jcp

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(New page: 200px<br /><applet load="2jcp" size="450" color="white" frame="true" align="right" spinBox="true" caption="2jcp, resolution 1.30&Aring;" /> '''THE HYALURONAN BINDI...)
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[[Image:2jcp.gif|left|200px]]<br /><applet load="2jcp" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="2jcp, resolution 1.30&Aring;" />
 
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'''THE HYALURONAN BINDING DOMAIN OF MURINE CD44'''<br />
 
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==About this Structure==
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==The hyaluronan binding domain of murine CD44==
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2JCP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JCP OCA].
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<StructureSection load='2jcp' size='340' side='right'caption='[[2jcp]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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[[Category: Mus musculus]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2jcp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JCP FirstGlance]. <br>
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[[Category: Banerji, S.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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[[Category: Campbell, I.D.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcp OCA], [https://pdbe.org/2jcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jcp RCSB], [https://www.ebi.ac.uk/pdbsum/2jcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jcp ProSAT]</span></td></tr>
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[[Category: Day, A.J.]]
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</table>
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[[Category: Jackson, D.G.]]
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== Function ==
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[[Category: Mahoney, D.J.]]
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[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.
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[[Category: Noble, M.E.M.]]
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== Evolutionary Conservation ==
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[[Category: Wright, A.J.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: alternative splicing]]
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Check<jmol>
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[[Category: antigen]]
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<jmolCheckbox>
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[[Category: blood group antigen]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jc/2jcp_consurf.spt"</scriptWhenChecked>
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[[Category: c-type lectin]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: cell adhesion]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: extracellular matrix]]
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</jmolCheckbox>
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[[Category: glycoprotein]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jcp ConSurf].
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[[Category: hyauronan]]
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<div style="clear:both"></div>
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[[Category: lectin]]
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[[Category: link-domain]]
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[[Category: membrane]]
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[[Category: phosphorylation]]
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[[Category: polymorphism]]
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[[Category: proteoglycan]]
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[[Category: pyrrolidone carboxylic acid]]
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[[Category: receptor]]
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[[Category: sugar- binding]]
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[[Category: sulfation]]
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[[Category: transmembrane]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 12:35:36 2007''
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==See Also==
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*[[CD44|CD44]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Banerji S]]
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[[Category: Campbell ID]]
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[[Category: Day AJ]]
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[[Category: Jackson DG]]
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[[Category: Mahoney DJ]]
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[[Category: Noble MEM]]
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[[Category: Wright AJ]]

Current revision

The hyaluronan binding domain of murine CD44

PDB ID 2jcp

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OCA

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