Sandbox29
From Proteopedia
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Created by Lori Mathis | Created by Lori Mathis | ||
| - | 1eve is a protein that is a drug used to prevent Alzheimer disease. The <scene name='Sandbox29/1eve/1'>overall structure</scene> of 1EVE contains | + | 1eve is a protein that is a drug used to prevent Alzheimer disease. The <scene name='Sandbox29/1eve/1'>overall structure</scene> of 1EVE contains 2 types of amphipathic elements; 15 <scene name='Sandbox29/Evebeta/1'>beta sheets</scene> and 16 <scene name='Sandbox29/Evealpha/1'>alpha helices</scene>. 1eve is a fairly standard molecule in the sense that the |
| - | <scene name='Sandbox29/Hydrophobic/1'>hydrophic</scene> aspects of the protein are well-maintained on the inside, while the hydrophillic portions are around the outside. 1eve has an active name called Acetylcholinesterase, which has a ligand called Aricept. 1eve is considered an AChE inhibitor, in which it has a high affinity for. The overall protein itself was created by a Japanese corporation called the Eisai Company. | + | <scene name='Sandbox29/Hydrophobic/1'>hydrophic</scene> aspects of the protein are well-maintained on the inside, while the hydrophillic portions are around the outside. 1eve has an active name called Acetylcholinesterase, which has a ligand called Aricept. There is an |
| + | <scene name='Sandbox29/Active_site/1'>active site</scene> in the middle of the molecule. 1eve is considered an AChE inhibitor, in which it has a high affinity for. The overall protein itself was created by a Japanese corporation called the Eisai Company. | ||
{{STRUCTURE_1eve | PDB=1eve | SCENE= }} | {{STRUCTURE_1eve | PDB=1eve | SCENE= }} | ||
Current revision
1EVE
This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!
Created by Lori Mathis
1eve is a protein that is a drug used to prevent Alzheimer disease. The of 1EVE contains 2 types of amphipathic elements; 15 and 16 . 1eve is a fairly standard molecule in the sense that the aspects of the protein are well-maintained on the inside, while the hydrophillic portions are around the outside. 1eve has an active name called Acetylcholinesterase, which has a ligand called Aricept. There is an in the middle of the molecule. 1eve is considered an AChE inhibitor, in which it has a high affinity for. The overall protein itself was created by a Japanese corporation called the Eisai Company.
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| 1eve, resolution 2.50Å () | |||||||||
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| Ligands: | , | ||||||||
| Activity: | Acetylcholinesterase, with EC number 3.1.1.7 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Reference to the Proteopedia pages dedicated to 1EVE, contributors are Eran Hodis, Joel L. Sussman, OCA, Wayne Decatur
