2zzj
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of endo-beta-1,4-glucuronan lyase from fungus Trichoderma reesei== | |
| + | <StructureSection load='2zzj' size='340' side='right'caption='[[2zzj]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2zzj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_13631 Atcc 13631]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZZJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZZJ FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=51453 ATCC 13631])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glucuronan_lyase Glucuronan lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.2.14 4.2.2.14] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zzj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zzj OCA], [https://pdbe.org/2zzj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zzj RCSB], [https://www.ebi.ac.uk/pdbsum/2zzj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zzj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zz/2zzj_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zzj ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of endo-beta-(1-->4)-glucuronan lyase from Trichoderma reesei (TrGL) has been determined at 1.8A resolution as the first three-dimensional structure of polysaccharide lyase (PL) family 20. TrGL has a typical beta-jelly roll fold, which is similar to glycoside hydrolase family 16 and PL7 enzymes. A calcium ion is bound to the site far from the cleft and appears to contribute to the stability. There are several completely conserved residues in the cleft. Possible catalytic residues are predicted based on structural comparison with PL7 alginate lyase A1-II'. | ||
| - | + | Crystal structure of polysaccharide lyase family 20 endo-beta-1,4-glucuronan lyase from the filamentous fungus Trichoderma reesei.,Konno N, Ishida T, Igarashi K, Fushinobu S, Habu N, Samejima M, Isogai A FEBS Lett. 2009 Apr 17;583(8):1323-6. Epub 2009 Mar 22. PMID:19306878<ref>PMID:19306878</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 2zzj" style="background-color:#fffaf0;"></div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Atcc 13631]] | ||
| + | [[Category: Glucuronan lyase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fushinobu, S]] | ||
| + | [[Category: Habu, N]] | ||
| + | [[Category: Igarashi, K]] | ||
| + | [[Category: Ishida, T]] | ||
| + | [[Category: Isogai, A]] | ||
| + | [[Category: Konno, N]] | ||
| + | [[Category: Samejima, M]] | ||
| + | [[Category: Beta-jelly roll]] | ||
| + | [[Category: Lyase]] | ||
Current revision
Crystal structure of endo-beta-1,4-glucuronan lyase from fungus Trichoderma reesei
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Categories: Atcc 13631 | Glucuronan lyase | Large Structures | Fushinobu, S | Habu, N | Igarashi, K | Ishida, T | Isogai, A | Konno, N | Samejima, M | Beta-jelly roll | Lyase
