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3gc2

From Proteopedia

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(New page: '''Unreleased structure''' The entry 3gc2 is ON HOLD Authors: Minasov, G., Wawrzak, Z., Skarina, T., Onopriyenko, O., Scott, P., Savchenko, A., Anderson, W.F., Center for Structural Gen...)
Current revision (08:01, 9 March 2022) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3gc2 is ON HOLD
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==1.85 Angstrom Crystal Structure of O-succinylbenzoate Synthase from Salmonella typhimurium in Complex with Succinic Acid==
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<StructureSection load='3gc2' size='340' side='right'caption='[[3gc2]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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Authors: Minasov, G., Wawrzak, Z., Skarina, T., Onopriyenko, O., Scott, P., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3gc2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GC2 FirstGlance]. <br>
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Description: 1.85 Angstrom Crystal Structure of O-succinylbenzoate Synthase from Salmonella typhimurium in Complex with Succinic Acid
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 11 11:11:11 2009''
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/o-succinylbenzoate_synthase o-succinylbenzoate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.113 4.2.1.113] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gc2 OCA], [https://pdbe.org/3gc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gc2 RCSB], [https://www.ebi.ac.uk/pdbsum/3gc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gc2 ProSAT], [https://www.topsan.org/Proteins/CSGID/3gc2 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/MENC_SALTY MENC_SALTY]] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).[HAMAP-Rule:MF_00470]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gc/3gc2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gc2 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: O-succinylbenzoate synthase]]
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[[Category: Anderson, W F]]
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[[Category: Structural genomic]]
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[[Category: Minasov, G]]
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[[Category: Onopriyenko, O]]
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[[Category: Peterson, S N]]
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[[Category: Savchenko, A]]
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[[Category: Skarina, T]]
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[[Category: Wawrzak, Z]]
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[[Category: Csgid]]
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[[Category: Idp00994]]
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[[Category: Lyase]]
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[[Category: Magnesium]]
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[[Category: Menaquinone biosynthesis]]
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[[Category: Metal-binding]]
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[[Category: Succinic acid]]

Current revision

1.85 Angstrom Crystal Structure of O-succinylbenzoate Synthase from Salmonella typhimurium in Complex with Succinic Acid

PDB ID 3gc2

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