Sandbox11

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<B>This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!</B>
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<!--
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Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page.
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Or use the four-green-boxes-button to insert scrollable text adjacent
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''K Sniffen 3/3/09, Keith Barbato, Jonathan Rymasz 3/18/09''
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to a Jmol applet. Check out the other buttons as well!
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-->
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{{STRUCTURE_1lds | PDB=1lds | SCENE= }}
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p53 Tumor Supressor gene/HOX gene?
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==Name==
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===please do not edit this sandbox unless you are part of La Canada High School Protein DNA Institute===
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beta-2-microglobulin
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== Basic ==
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===this is level 3===
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==About this Structure==
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this is text
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This protein consists of seven <scene name='Sandbox11/Beta-2-microglobulin/1'>Beta-sheets</scene> shown here in purple. It also has a small <scene name='Sandbox11/Beta_2_microglobulin/1'>alpha-helix</scene> on the surface of the protein shown in teal. Notice also, the <scene name='Sandbox11/Ligand_of_beta_2-microglobulin/1'>ligand</scene>, which allows for binding to occur. Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells (Gussow et al., 1987 [PubMed 3312414])[1]
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Here's a <scene name='Sandbox11/Disulfide_bond/1'>disulfide</scene>
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bond!!
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There is a hydrophobic element to B2M. When all of the most hydrophobic residues are selected, it can be clearly seen that there is a <scene name='Sandbox11/Beta-2-m_hydrophobic_core/1'>Hydrophobic Core</scene> between the two Beta sheets. Speculation could say that it has evolved in this manner to protect the <scene name='Sandbox11/Disulfide_bond/1'>disulfide bond</scene>.
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==References==
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[http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=567]Entrez Gene: B2M
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[http://www.russell.embl.de/aas/hydrophobic.html] list of hydrophobic amino acids
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Current revision

p53 Tumor Supressor gene/HOX gene?

please do not edit this sandbox unless you are part of La Canada High School Protein DNA Institute

Basic

this is level 3

this is text

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