2jaj

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{{Seed}}
 
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[[Image:2jaj.png|left|200px]]
 
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<!--
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==DDAH1 complexed with L-257==
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The line below this paragraph, containing "STRUCTURE_2jaj", creates the "Structure Box" on the page.
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<StructureSection load='2jaj' size='340' side='right'caption='[[2jaj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2jaj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JAJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D20:N~5~-{IMINO[(2-METHOXYETHYL)AMINO]METHYL}-L-ORNITHINE'>D20</scene></td></tr>
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{{STRUCTURE_2jaj| PDB=2jaj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jaj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jaj OCA], [https://pdbe.org/2jaj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jaj RCSB], [https://www.ebi.ac.uk/pdbsum/2jaj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jaj ProSAT]</span></td></tr>
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</table>
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===DDAH1 COMPLEXED WITH L-257===
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== Function ==
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[https://www.uniprot.org/uniprot/DDAH1_HUMAN DDAH1_HUMAN] Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_17273169}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17273169 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2jaj_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17273169}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2JAJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAJ OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jaj ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:17273169</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Dimethylargininase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Hara, B P.O.]]
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[[Category: Large Structures]]
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[[Category: Leiper, J M.]]
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[[Category: Leiper JM]]
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[[Category: Mcdonald, N Q.]]
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[[Category: McDonald NQ]]
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[[Category: Murray-Rust, J.]]
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[[Category: Murray-Rust J]]
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[[Category: Rossiter, S.]]
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[[Category: O'Hara BP]]
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[[Category: Vallance, P.]]
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[[Category: Rossiter S]]
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[[Category: Ddah]]
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[[Category: Vallance P]]
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[[Category: Hydrolase]]
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[[Category: Nitric oxide synthase inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 11:33:43 2009''
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Current revision

DDAH1 complexed with L-257

PDB ID 2jaj

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OCA

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