2rq9
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2rq9 is ON HOLD Authors: Enomoto, M., Xiang, L., Ishii, T., Tochio, N., Hosoda, K., Inoue, Y., Nameki, N., Wakamatsu, K. Description: Solution stru...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new== | |
| + | <StructureSection load='2rq9' size='340' side='right'caption='[[2rq9]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2rq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQ9 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rq9 OCA], [https://pdbe.org/2rq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rq9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rq9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rq/2rq9_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rq9 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Enomoto M]] | ||
| + | [[Category: Hosoda K]] | ||
| + | [[Category: Inoue Y]] | ||
| + | [[Category: Ishii T]] | ||
| + | [[Category: Nameki N]] | ||
| + | [[Category: Tochio N]] | ||
| + | [[Category: Wakamatsu K]] | ||
| + | [[Category: Xiang L]] | ||
Current revision
Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new
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Categories: Homo sapiens | Large Structures | Enomoto M | Hosoda K | Inoue Y | Ishii T | Nameki N | Tochio N | Wakamatsu K | Xiang L
