3gle
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3gle is ON HOLD until Paper Publication Authors: Kang, H.J., Baker, E.N. Description: Crystal Structure of the Major Pilin from Streptococcus pyoge...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the Major Pilin from Streptococcus pyogenes N168A mutant== | |
| + | <StructureSection load='3gle' size='340' side='right'caption='[[3gle]], [[Resolution|resolution]] 2.19Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3gle]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_serotype_M1 Streptococcus pyogenes serotype M1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GLE FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gle OCA], [https://pdbe.org/3gle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gle RCSB], [https://www.ebi.ac.uk/pdbsum/3gle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gle ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PILIN_STRP1 PILIN_STRP1] Major component of the pilus. A stack of the pilin subunits, joined by intermolecular isopeptide bonds, forms the pilus. The pilus is required for bacterial adhesion to host cells, for bacterial aggregation, and for biofilm formation.<ref>PMID:17501921</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gl/3gle_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gle ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Pilin 3D structures|Pilin 3D structures]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Streptococcus pyogenes serotype M1]] | ||
| + | [[Category: Baker EN]] | ||
| + | [[Category: Kang HJ]] | ||
Current revision
Crystal Structure of the Major Pilin from Streptococcus pyogenes N168A mutant
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