3cw1

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{{Seed}}
 
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[[Image:3cw1.jpg|left|200px]]
 
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==Crystal Structure of Human Spliceosomal U1 snRNP==
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The line below this paragraph, containing "STRUCTURE_3cw1", creates the "Structure Box" on the page.
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<StructureSection load='3cw1' size='340' side='right'caption='[[3cw1]], [[Resolution|resolution]] 5.49&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3cw1]] is a 40 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CW1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 5.493&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3cw1| PDB=3cw1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cw1 OCA], [https://pdbe.org/3cw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cw1 RCSB], [https://www.ebi.ac.uk/pdbsum/3cw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cw1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SMD3_HUMAN SMD3_HUMAN] Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.<ref>PMID:11574479</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cw/3cw1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cw1 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Human Spliceosomal U1 snRNP===
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==See Also==
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*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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3CW1 is a 40 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW1 OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:10025403</ref><ref group="xtra">PMID:15312772</ref><ref group="xtra">PMID:10931958</ref><ref group="xtra">PMID:7984237</ref><ref group="xtra">PMID:2374709</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Krummel, D A.Pomeranz.]]
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[[Category: Large Structures]]
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[[Category: Leung, A K.W.]]
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[[Category: Leung AK]]
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[[Category: Li, J.]]
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[[Category: Li J]]
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[[Category: Nagai, K.]]
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[[Category: Nagai K]]
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[[Category: Oubridge, C.]]
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[[Category: Oubridge C]]
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[[Category: 5' splice site]]
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[[Category: Pomeranz Krummel DA]]
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[[Category: Pre-mrna splicing]]
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[[Category: Rna recognition motif]]
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[[Category: Rna-binding domain]]
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[[Category: Sm fold]]
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[[Category: Spliceosome]]
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[[Category: Zinc finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:24:11 2009''
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Current revision

Crystal Structure of Human Spliceosomal U1 snRNP

PDB ID 3cw1

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