2ztb

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{{Seed}}
 
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[[Image:2ztb.png|left|200px]]
 
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==Crystal structure of the parasporin-2 Bacillus thuringiensis toxin that recognizes cancer cells==
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The line below this paragraph, containing "STRUCTURE_2ztb", creates the "Structure Box" on the page.
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<StructureSection load='2ztb' size='340' side='right'caption='[[2ztb]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ztb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis_serovar_dakota Bacillus thuringiensis serovar dakota]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZTB FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LU:LUTETIUM+(III)+ION'>LU</scene></td></tr>
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{{STRUCTURE_2ztb| PDB=2ztb | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ztb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ztb OCA], [https://pdbe.org/2ztb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ztb RCSB], [https://www.ebi.ac.uk/pdbsum/2ztb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ztb ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the parasporin-2 Bacillus thuringiensis toxin that recognizes cancer cells===
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== Function ==
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[https://www.uniprot.org/uniprot/Q7WZI1_BACUA Q7WZI1_BACUA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_19094993}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 19094993 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zt/2ztb_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_19094993}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2ZTB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thuringiensis_serovar_dakota Bacillus thuringiensis serovar dakota]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZTB OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ztb ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal Structure of the Parasporin-2 Bacillus thuringiensis Toxin That Recognizes Cancer Cells., Akiba T, Abe Y, Kitada S, Kusaka Y, Ito A, Ichimatsu T, Katayama H, Akao T, Higuchi K, Mizuki E, Ohba M, Kanai R, Harata K, J Mol Biol. 2008 Dec 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19094993 19094993]
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</StructureSection>
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Crystallization of parasporin-2, a Bacillus thuringiensis crystal protein with selective cytocidal activity against human cells., Akiba T, Abe Y, Kitada S, Kusaka Y, Ito A, Ichimatsu T, Katayama H, Akao T, Higuchi K, Mizuki E, Ohba M, Kanai R, Harata K, Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 2):2355-7. Epub, 2004 Nov 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15583389 15583389]
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A Bacillus thuringiensis crystal protein with selective cytocidal action to human cells., Ito A, Sasaguri Y, Kitada S, Kusaka Y, Kuwano K, Masutomi K, Mizuki E, Akao T, Ohba M, J Biol Chem. 2004 May 14;279(20):21282-6. Epub 2004 Mar 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15026424 15026424]
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[[Category: Bacillus thuringiensis serovar dakota]]
[[Category: Bacillus thuringiensis serovar dakota]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Akiba T]]
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[[Category: Beta-hairpin]]
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[[Category: Toxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 21:04:19 2009''
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Current revision

Crystal structure of the parasporin-2 Bacillus thuringiensis toxin that recognizes cancer cells

PDB ID 2ztb

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