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3goc
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:3goc.jpg|left|200px]] | ||
| - | < | + | ==Crystal structure of the Endonuclease V (SAV1684) from Streptomyces avermitilis. Northeast Structural Genomics Consortium Target SvR196== |
| - | + | <StructureSection load='3goc' size='340' side='right'caption='[[3goc]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3goc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avermitilis_MA-4680_=_NBRC_14893 Streptomyces avermitilis MA-4680 = NBRC 14893]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GOC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=YES:3-(2-HYDROXYETHYL)-2,2-BIS(HYDROXYMETHYL)PENTANE-1,5-DIOL'>YES</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3goc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3goc OCA], [https://pdbe.org/3goc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3goc RCSB], [https://www.ebi.ac.uk/pdbsum/3goc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3goc ProSAT], [https://www.topsan.org/Proteins/NESGC/3goc TOPSAN]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NFI_STRAW NFI_STRAW] DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity).[HAMAP-Rule:MF_00801] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/3goc_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3goc ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Endonuclease 3D structures|Endonuclease 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[Category: | + | [[Category: Streptomyces avermitilis MA-4680 = NBRC 14893]] |
| - | [[Category: | + | [[Category: Abashidze M]] |
| - | [[Category: Abashidze | + | [[Category: Acton TB]] |
| - | [[Category: Acton | + | [[Category: Chen CX]] |
| - | [[Category: Chen | + | [[Category: Cunningham K]] |
| - | [[Category: Cunningham | + | [[Category: Everett JK]] |
| - | [[Category: Everett | + | [[Category: Fang F]] |
| - | [[Category: Fang | + | [[Category: Forouhar F]] |
| - | [[Category: Forouhar | + | [[Category: Hunt JF]] |
| - | [[Category: Hunt | + | [[Category: Hussain M]] |
| - | [[Category: Hussain | + | [[Category: Ma L]] |
| - | [[Category: Ma | + | [[Category: Montelione GT]] |
| - | [[Category: Montelione | + | [[Category: Nair R]] |
| - | + | [[Category: Owens L]] | |
| - | [[Category: Nair | + | [[Category: Rost B]] |
| - | [[Category: Owens | + | [[Category: Seetharaman J]] |
| - | [[Category: Rost | + | [[Category: Tong L]] |
| - | [[Category: Seetharaman | + | [[Category: Xiao R]] |
| - | [[Category: Tong | + | |
| - | [[Category: Xiao | + | |
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Current revision
Crystal structure of the Endonuclease V (SAV1684) from Streptomyces avermitilis. Northeast Structural Genomics Consortium Target SvR196
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Categories: Large Structures | Streptomyces avermitilis MA-4680 = NBRC 14893 | Abashidze M | Acton TB | Chen CX | Cunningham K | Everett JK | Fang F | Forouhar F | Hunt JF | Hussain M | Ma L | Montelione GT | Nair R | Owens L | Rost B | Seetharaman J | Tong L | Xiao R
