This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2fem

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:23, 14 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2fem.png|left|200px]]
 
-
<!--
+
==Mutant R188M of the Cytidine Monophosphate Kinase From E. Coli==
-
The line below this paragraph, containing "STRUCTURE_2fem", creates the "Structure Box" on the page.
+
<StructureSection load='2fem' size='340' side='right'caption='[[2fem]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2fem]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FEM FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fem OCA], [https://pdbe.org/2fem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fem RCSB], [https://www.ebi.ac.uk/pdbsum/2fem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fem ProSAT]</span></td></tr>
-
{{STRUCTURE_2fem| PDB=2fem | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KCY_ECOLI KCY_ECOLI] ATP, dATP, and GTP are equally effective as phosphate donors. CMP and dCMP are the best phosphate acceptors.<ref>PMID:8190075</ref> <ref>PMID:7836281</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fe/2fem_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fem ConSurf].
 +
<div style="clear:both"></div>
-
===Mutant R188M of the Cytidine Monophosphate Kinase From E. Coli===
+
==See Also==
-
 
+
*[[Cytidine monophosphate kinase|Cytidine monophosphate kinase]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_17542990}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 17542990 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_17542990}}
+
-
 
+
-
==About this Structure==
+
-
2FEM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FEM OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:17542990</ref><references group="xtra"/>
+
-
[[Category: Cytidylate kinase]]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Alexov, E.]]
+
[[Category: Large Structures]]
-
[[Category: Barzu, O.]]
+
[[Category: Alexov E]]
-
[[Category: Bertrand, T.]]
+
[[Category: Barzu O]]
-
[[Category: Briozzo, P.]]
+
[[Category: Bertrand T]]
-
[[Category: Bucurenci, N.]]
+
[[Category: Briozzo P]]
-
[[Category: Gilles, A M.]]
+
[[Category: Bucurenci N]]
-
[[Category: Munier-Lehmann, H.]]
+
[[Category: Gilles AM]]
-
[[Category: Ofiteru, A.]]
+
[[Category: Munier-Lehmann H]]
-
[[Category: Tourneux, L.]]
+
[[Category: Ofiteru A]]
-
[[Category: Nucleotide monophosphate kinase]]
+
[[Category: Tourneux L]]
-
[[Category: Signaling protein]]
+
-
[[Category: Transferase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 15 09:26:03 2009''
+

Current revision

Mutant R188M of the Cytidine Monophosphate Kinase From E. Coli

PDB ID 2fem

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2fem"
Personal tools