2ela

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:50, 13 March 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2ela.png|left|200px]]
 
-
<!--
+
==Crystal Structure of the PTB domain of human APPL1==
-
The line below this paragraph, containing "STRUCTURE_2ela", creates the "Structure Box" on the page.
+
<StructureSection load='2ela' size='340' side='right'caption='[[2ela]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2ela]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ELA FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ela FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ela OCA], [https://pdbe.org/2ela PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ela RCSB], [https://www.ebi.ac.uk/pdbsum/2ela PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ela ProSAT]</span></td></tr>
-
{{STRUCTURE_2ela| PDB=2ela | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Crystal Structure of the PTB domain of human APPL1===
+
[https://www.uniprot.org/uniprot/DP13A_HUMAN DP13A_HUMAN] Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.<ref>PMID:10490823</ref> <ref>PMID:15016378</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_17502098}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 17502098 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/2ela_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_17502098}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ela ConSurf].
-
2ELA is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELA OCA].
+
<div style="clear:both"></div>
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:17502098</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Dong, L Q.]]
+
[[Category: Large Structures]]
-
[[Category: Li, J.]]
+
[[Category: Dong LQ]]
-
[[Category: Liu, F.]]
+
[[Category: Li J]]
-
[[Category: Mao, X.]]
+
[[Category: Liu F]]
-
[[Category: Tong, L.]]
+
[[Category: Mao X]]
-
[[Category: Appl]]
+
[[Category: Tong L]]
-
[[Category: Cell cycle]]
+
-
[[Category: Ptb domain]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Apr 19 08:16:53 2009''
+

Current revision

Crystal Structure of the PTB domain of human APPL1

PDB ID 2ela

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ela"
Personal tools