1w8x

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{{Seed}}
 
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[[Image:1w8x.png|left|200px]]
 
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==Structural analysis of PRD1==
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The line below this paragraph, containing "STRUCTURE_1w8x", creates the "Structure Box" on the page.
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<SX load='1w8x' size='340' side='right' viewer='molstar' caption='[[1w8x]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1w8x]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_PRD1 Enterobacteria phage PRD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W8X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W8X FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w8x OCA], [https://pdbe.org/1w8x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w8x RCSB], [https://www.ebi.ac.uk/pdbsum/1w8x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w8x ProSAT]</span></td></tr>
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{{STRUCTURE_1w8x| PDB=1w8x | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAPSD_BPPRD CAPSD_BPPRD] Major capsid protein self-assembles to form an icosahedral capsid with a pseudo T=25 symmetry, about 66 nm in diameter, and consisting of 240 capsid proteins trimers. The capsid encapsulates an inner membrane and the genomic dsDNA genome. The major coat protein P3 and two assembly factors (P10 and P17) are needed during the assembly of the virus particle inside the host cell, when the capsid protein multimers are capable of enclosing the host-derived membrane, containing the virus-encoded membrane-associated proteins.
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of the membrane-containing bacteriophage PRD1 has been determined by X-ray crystallography at about 4 A resolution. Here we describe the structure and location of proteins P3, P16, P30 and P31. Different structural proteins seem to have specialist roles in controlling virus assembly. The linearly extended P30 appears to nucleate the formation of the icosahedral facets (composed of trimers of the major capsid protein, P3) and acts as a molecular tape-measure, defining the size of the virus and cementing the facets together. Pentamers of P31 form the vertex base, interlocking with subunits of P3 and interacting with the membrane protein P16. The architectural similarities with adenovirus and one of the largest known virus particles PBCV-1 support the notion that the mechanism of assembly of PRD1 is scaleable and applies across the major viral lineage formed by these viruses.
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===STRUCTURAL ANALYSIS OF PRD1===
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Insights into assembly from structural analysis of bacteriophage PRD1.,Abrescia NG, Cockburn JJ, Grimes JM, Sutton GC, Diprose JM, Butcher SJ, Fuller SD, San Martin C, Burnett RM, Stuart DI, Bamford DH, Bamford JK Nature. 2004 Nov 4;432(7013):68-74. PMID:15525981<ref>PMID:15525981</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 1w8x" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15525981 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15525981}}
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__TOC__
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</SX>
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==About this Structure==
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[[Category: Enterobacteria phage PRD1]]
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1W8X is a 15 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterobacteria_phage_prd1 Enterobacteria phage prd1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W8X OCA].
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[[Category: Large Structures]]
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[[Category: Abrescia NGA]]
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==Reference==
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[[Category: Bamford DH]]
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<ref group="xtra">PMID:15525981</ref><references group="xtra"/>
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[[Category: Bamford JKH]]
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[[Category: Enterobacteria phage prd1]]
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[[Category: Burnett RM]]
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[[Category: Abrescia, N G.A.]]
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[[Category: Butcher SJ]]
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[[Category: Bamford, D H.]]
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[[Category: Cockburn JJB]]
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[[Category: Bamford, J K.H.]]
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[[Category: Diprose JM]]
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[[Category: Burnett, R M.]]
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[[Category: Fuller SD]]
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[[Category: Butcher, S J.]]
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[[Category: Grimes JM]]
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[[Category: Cockburn, J J.B.]]
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[[Category: San Martin C]]
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[[Category: Diprose, J M.]]
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[[Category: Stuart DI]]
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[[Category: Fuller, S D.]]
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[[Category: Sutton GC]]
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[[Category: Grimes, J M.]]
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[[Category: Martin, C San.]]
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[[Category: Stuart, D I.]]
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[[Category: Sutton, G C.]]
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[[Category: Icosahedral virus]]
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[[Category: P16 membrane protein]]
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[[Category: P3 major capsid protein]]
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[[Category: P30 tape measure]]
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[[Category: P31 penton protein]]
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[[Category: Virus]]
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[[Category: Virus/viral protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 10:38:25 2009''
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Current revision

Structural analysis of PRD1

1w8x, resolution 4.20Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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