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3cuf

From Proteopedia

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{{Seed}}
 
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[[Image:3cuf.jpg|left|200px]]
 
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==Cellulomonas fimi Xylanase/Cellulase Cex (Cf Xyn10A) in complex with cellobiose-like isofagomine==
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The line below this paragraph, containing "STRUCTURE_3cuf", creates the "Structure Box" on the page.
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<StructureSection load='3cuf' size='340' side='right'caption='[[3cuf]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3cuf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cellulomonas_fimi Cellulomonas fimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CUF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9MR:(3R,4R,5R)-3-HYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-4-YL+BETA-D-GLUCOPYRANOSIDE'>9MR</scene></td></tr>
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{{STRUCTURE_3cuf| PDB=3cuf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cuf OCA], [https://pdbe.org/3cuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cuf RCSB], [https://www.ebi.ac.uk/pdbsum/3cuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cuf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GUX_CELFI GUX_CELFI] Hydrolyzes both cellulose and xylan. Has also weak endoglucanase activity. The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/3cuf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cuf ConSurf].
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<div style="clear:both"></div>
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===Cellulomonas fimi Xylanase/Cellulase Cex (Cf Xyn10A) in complex with cellobiose-like isofagomine===
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==See Also==
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*[[Glucanase 3D structures|Glucanase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3CUF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Cellulomonas_fimi Cellulomonas fimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CUF OCA].
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[[Category: Cellulomonas fimi]]
[[Category: Cellulomonas fimi]]
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[[Category: Cellulose 1,4-beta-cellobiosidase]]
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[[Category: Large Structures]]
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[[Category: Kuntz, D A.]]
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[[Category: Kuntz DA]]
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[[Category: Rose, D R.]]
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[[Category: Rose DR]]
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[[Category: Saul, M.]]
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[[Category: Saul M]]
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[[Category: Cex]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Isofagomine inhibitor]]
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[[Category: Tim barrel]]
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[[Category: Xylanase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 11:29:56 2009''
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Current revision

Cellulomonas fimi Xylanase/Cellulase Cex (Cf Xyn10A) in complex with cellobiose-like isofagomine

PDB ID 3cuf

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