3cuu

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{{Seed}}
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==Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamides==
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[[Image:3cuu.jpg|left|200px]]
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<StructureSection load='3cuu' size='340' side='right' caption='[[3cuu]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3cuu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CUU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CUU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=376:N-[(NAPHTHALEN-1-YLAMINO)(OXO)ACETYL]-BETA-D-GLUCOPYRANOSYLAMINE'>376</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cut|3cut]], [[3cuv|3cuv]], [[3cuw|3cuw]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cuu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cuu OCA], [http://pdbe.org/3cuu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cuu RCSB], [http://www.ebi.ac.uk/pdbsum/3cuu PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT]] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/3cuu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cuu ConSurf].
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<div style="clear:both"></div>
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<!--
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==See Also==
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The line below this paragraph, containing "STRUCTURE_3cuu", creates the "Structure Box" on the page.
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*[[Glycogen Phosphorylase|Glycogen Phosphorylase]]
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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__TOC__
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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</StructureSection>
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or leave the SCENE parameter empty for the default display.
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-->
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{{STRUCTURE_3cuu| PDB=3cuu | SCENE= }}
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===Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamides===
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==About this Structure==
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3CUU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CUU OCA].
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[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Phosphorylase]]
[[Category: Phosphorylase]]
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[[Category: Chrysina, E D.]]
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[[Category: Chrysina, E D]]
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[[Category: Kyritsi, C.]]
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[[Category: Kyritsi, C]]
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[[Category: Leonidas, D D.]]
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[[Category: Leonidas, D D]]
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[[Category: Oikonomakos, N G.]]
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[[Category: Oikonomakos, N G]]
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[[Category: Zographos, S E.]]
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[[Category: Zographos, S E]]
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[[Category: Acetylation]]
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[[Category: Allosteric enzyme]]
[[Category: Allosteric enzyme]]
[[Category: Carbohydrate metabolism]]
[[Category: Carbohydrate metabolism]]
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[[Category: Pyridoxal phosphate]]
[[Category: Pyridoxal phosphate]]
[[Category: Rational inhibitor design]]
[[Category: Rational inhibitor design]]
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[[Category: Structure]]
 
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 11:31:20 2009''
 

Current revision

Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamides

3cuu, resolution 2.30Å

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