Sandbox 70

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{{Template:McQuaid Sandbox Reservation}}
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==This is a placeholder==
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== About Topoisomerases ==
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This is a placeholder text to help you get started in
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placing a Jmol applet on your page. At any time, click
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"Show Preview" at the bottom of this page to see how it goes.
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Replace the PDB id (use lowercase!) after the STRUCTURE_ and after PDB= to load
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You may wonder about the structure of DNA such as is it tangled or does it become stressed? Well the answer is yes but there a protein that relaxes and untangles DNA,it is called Topoisomerases.Topoisomerases is a protein that untangles and relax DNA.
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and display another structure.
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{{STRUCTURE_3cin | =3cin | SCENE= }}
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== Function ==
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Topoisomerases wraps itself around DNA and makes a cut in one strand. While holding that damaged area, the enzyme allows the helix to spin, relaxing any tangled or untangled. After DNA relaxed,topoisomerase reconnects the broken strand, then returning DNA double helix back.
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You may wonder do DNA get tangle or do
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they get stressed?Well the answer is yes
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but there a protein that relaxes and
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== Structural Properties ==
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untangles DNA,it called Topoisomerases.
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Topoisomerases is mostly apla heliex,it also has beta sheet's
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Topoisomerases is a protein that untangle
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and that concect each other. So there primary
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and relax DNA.
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and secondary and 3rd level and maybe the 4th levl of structure
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{{STRUCTURE_1a36| PDB=1a36| SCENE= }}

Current revision

Please do NOT make changes to this Sandbox until after April 30, 2009. Sandboxes 60-80 are reserved until then for use by students of East High, Buffalo NY.

About Topoisomerases

You may wonder about the structure of DNA such as is it tangled or does it become stressed? Well the answer is yes but there a protein that relaxes and untangles DNA,it is called Topoisomerases.Topoisomerases is a protein that untangles and relax DNA.

Function

Topoisomerases wraps itself around DNA and makes a cut in one strand. While holding that damaged area, the enzyme allows the helix to spin, relaxing any tangled or untangled. After DNA relaxed,topoisomerase reconnects the broken strand, then returning DNA double helix back.


Structural Properties

Topoisomerases is mostly apla heliex,it also has beta sheet's and that concect each other. So there primary 

and secondary and 3rd level and maybe the 4th levl of structure


PDB ID 1a36

Drag the structure with the mouse to rotate
1a36, resolution 2.80Å ()
Activity: DNA topoisomerase, with EC number 5.99.1.2
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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