2rec

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(New page: 200px<br /><applet load="2rec" size="450" color="white" frame="true" align="right" spinBox="true" caption="2rec" /> '''RECA HEXAMER MODEL, ELECTRON MICROSCOPY'''<b...)
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[[Image:2rec.gif|left|200px]]<br /><applet load="2rec" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="2rec" />
 
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'''RECA HEXAMER MODEL, ELECTRON MICROSCOPY'''<br />
 
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==Overview==
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==RECA HEXAMER MODEL, ELECTRON MICROSCOPY==
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The RecA protein forms a hexameric ring that is similar to the core of the, F1-ATPase. Several lines of evidence suggest that this hexamer may be a, structural homologue of ring helicases.
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<StructureSection load='2rec' size='340' side='right'caption='[[2rec]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2rec]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2REC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2REC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rec OCA], [https://pdbe.org/2rec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rec RCSB], [https://www.ebi.ac.uk/pdbsum/2rec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rec ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RECA_ECOLI RECA_ECOLI] Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.[HAMAP-Rule:MF_00268]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/re/2rec_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rec ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The RecA protein forms a hexameric ring that is similar to the core of the F1-ATPase. Several lines of evidence suggest that this hexamer may be a structural homologue of ring helicases.
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==About this Structure==
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The RecA hexamer is a structural homologue of ring helicases.,Yu X, Egelman EH Nat Struct Biol. 1997 Feb;4(2):101-4. PMID:9033586<ref>PMID:9033586</ref>
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2REC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2REC OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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The RecA hexamer is a structural homologue of ring helicases., Yu X, Egelman EH, Nat Struct Biol. 1997 Feb;4(2):101-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9033586 9033586]
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</div>
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[[Category: Escherichia coli]]
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<div class="pdbe-citations 2rec" style="background-color:#fffaf0;"></div>
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[[Category: Single protein]]
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[[Category: Egelman, E.H.]]
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[[Category: Yu, X.]]
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[[Category: atp-binding]]
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[[Category: dna damage]]
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[[Category: dna recombination]]
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[[Category: dna-binding]]
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[[Category: helicase]]
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[[Category: sos response]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 13:57:25 2007''
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==See Also==
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*[[3D structures of recombinase A|3D structures of recombinase A]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Egelman EH]]
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[[Category: Yu X]]

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RECA HEXAMER MODEL, ELECTRON MICROSCOPY

PDB ID 2rec

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