2wh5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2wh5 is ON HOLD Authors: Yue, W.W., Shafqat, N., Ugochukwu, E., Savitsky, P., Johansson, C., Salah, E., Roos, A.K., Chaikuad, A., vonDelft, F., Arro...) |
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA== | |
- | + | <StructureSection load='2wh5' size='340' side='right'caption='[[2wh5]], [[Resolution|resolution]] 2.60Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2wh5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WH5 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ST9:STEAROYL-COENZYME+A'>ST9</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh5 OCA], [https://pdbe.org/2wh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wh5 RCSB], [https://www.ebi.ac.uk/pdbsum/2wh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh5 ProSAT]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ACBD4_HUMAN ACBD4_HUMAN] Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wh/2wh5_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wh5 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Arrowsmith C]] | ||
+ | [[Category: Bountra C]] | ||
+ | [[Category: Chaikuad A]] | ||
+ | [[Category: Edwards A]] | ||
+ | [[Category: Johansson C]] | ||
+ | [[Category: Oppermann U]] | ||
+ | [[Category: Roos AK]] | ||
+ | [[Category: Salah E]] | ||
+ | [[Category: Savitsky P]] | ||
+ | [[Category: Shafqat N]] | ||
+ | [[Category: Ugochukwu E]] | ||
+ | [[Category: Weigelt J]] | ||
+ | [[Category: Yue WW]] | ||
+ | [[Category: Von Delft F]] |
Current revision
Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Bountra C | Chaikuad A | Edwards A | Johansson C | Oppermann U | Roos AK | Salah E | Savitsky P | Shafqat N | Ugochukwu E | Weigelt J | Yue WW | Von Delft F