3cz3

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{{Seed}}
 
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[[Image:3cz3.jpg|left|200px]]
 
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==Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA==
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The line below this paragraph, containing "STRUCTURE_3cz3", creates the "Structure Box" on the page.
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<StructureSection load='3cz3' size='340' side='right'caption='[[3cz3]], [[Resolution|resolution]] 3.23&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3cz3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_aspermy_virus Tomato aspermy virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CZ3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.23&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz3 OCA], [https://pdbe.org/3cz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cz3 RCSB], [https://www.ebi.ac.uk/pdbsum/3cz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cz3 ProSAT]</span></td></tr>
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{{STRUCTURE_3cz3| PDB=3cz3 | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA===
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[https://www.uniprot.org/uniprot/2B_TAV 2B_TAV] Acts as suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Forms a homodimer to measure siRNA duplex in a length-preferencemode. Binds to both siRNA duplexes (19bp) and long siRNA duplexes (30bp).<ref>PMID:10329615</ref> <ref>PMID:8291242</ref> <ref>PMID:9010309</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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3CZ3 is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Tomato_aspermy_virus Tomato aspermy virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ3 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/3cz3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cz3 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Tomato aspermy virus]]
[[Category: Tomato aspermy virus]]
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[[Category: Ding, S W.]]
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[[Category: Ding SW]]
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[[Category: Li, F.]]
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[[Category: Li F]]
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[[Category: Ma, J B.]]
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[[Category: Ma JB]]
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[[Category: Patel, D J.]]
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[[Category: Patel DJ]]
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[[Category: Coiled coil]]
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[[Category: Nucleus]]
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[[Category: Protein-dsrna complex]]
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[[Category: Suppressor of rna silencing]]
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[[Category: Viral protein/rna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 11:25:44 2009''
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Current revision

Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA

PDB ID 3cz3

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