2e60

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{{Seed}}
 
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[[Image:2e60.png|left|200px]]
 
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==Solution structure of the surp1 domain in splicing factor, arginine/serine-rich 8==
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The line below this paragraph, containing "STRUCTURE_2e60", creates the "Structure Box" on the page.
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<StructureSection load='2e60' size='340' side='right'caption='[[2e60]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2e60]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E60 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e60 OCA], [https://pdbe.org/2e60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e60 RCSB], [https://www.ebi.ac.uk/pdbsum/2e60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e60 ProSAT], [https://www.topsan.org/Proteins/RSGI/2e60 TOPSAN]</span></td></tr>
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{{STRUCTURE_2e60| PDB=2e60 | SCENE= }}
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</table>
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== Function ==
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===Solution structure of the surp1 domain in splicing factor, arginine/serine-rich 8===
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[https://www.uniprot.org/uniprot/SFSWA_HUMAN SFSWA_HUMAN] Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10.<ref>PMID:8940107</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2E60 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E60 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/2e60_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e60 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: He, F.]]
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[[Category: Large Structures]]
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[[Category: Inoue, M.]]
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[[Category: He F]]
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[[Category: Kigawa, T.]]
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[[Category: Inoue M]]
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[[Category: Muto, Y.]]
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[[Category: Kigawa T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Muto Y]]
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[[Category: Shirouzu, M.]]
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[[Category: Shirouzu M]]
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[[Category: Terada, T.]]
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[[Category: Terada T]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nmr]]
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[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rna binding protein]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Surp domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 09:10:37 2009''
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Current revision

Solution structure of the surp1 domain in splicing factor, arginine/serine-rich 8

PDB ID 2e60

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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