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1mou

From Proteopedia

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{{Seed}}
 
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[[Image:1mou.png|left|200px]]
 
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==Crystal structure of Coral pigment==
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The line below this paragraph, containing "STRUCTURE_1mou", creates the "Structure Box" on the page.
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<StructureSection load='1mou' size='340' side='right'caption='[[1mou]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mou]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Montipora_efflorescens Montipora efflorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MOU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MOU FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CRQ:[2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC+ACID'>CRQ</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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{{STRUCTURE_1mou| PDB=1mou | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mou OCA], [https://pdbe.org/1mou PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mou RCSB], [https://www.ebi.ac.uk/pdbsum/1mou PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mou ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NFCP_MONEF NFCP_MONEF] Thought to play a role in photoprotection of the coral's resident symbiont microalgae's photosystems from photoinhibition caused by high light levels found near the surface of coral reefs.<ref>PMID:12595737</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mo/1mou_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mou ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Reef-building corals contain host pigments, termed pocilloporins, that function to regulate the light environment of their resident microalgae by acting as a photoprotectant in excessive sunlight. We have determined the crystal structure of an intensely blue, nonfluorescent pocilloporin to 2.2 A resolution and a genetically engineered fluorescent variant to 2.4 A resolution. The pocilloporin chromophore structure adopts a markedly different conformation in comparison with the DsRed chromophore, despite the chromophore sequences (Gln-Tyr-Gly) being identical; the tyrosine ring of the pocilloporin chromophore is noncoplanar and in the trans configuration. Furthermore, the fluorescent variant adopted a noncoplanar chromophore conformation. The data presented here demonstrates that the conformation of the chromophore is highly dependent on its immediate environment.
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===Crystal structure of Coral pigment===
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The 2.2 A crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation.,Prescott M, Ling M, Beddoe T, Oakley AJ, Dove S, Hoegh-Guldberg O, Devenish RJ, Rossjohn J Structure. 2003 Mar;11(3):275-84. PMID:12623015<ref>PMID:12623015</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_12623015}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1mou" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 12623015 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_12623015}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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1MOU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Montipora_efflorescens Montipora efflorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MOU OCA].
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==Reference==
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<ref group="xtra">PMID:12623015</ref><references group="xtra"/>
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[[Category: Montipora efflorescens]]
[[Category: Montipora efflorescens]]
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[[Category: Beddoe, T.]]
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[[Category: Beddoe T]]
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[[Category: Devenish, R J.]]
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[[Category: Devenish RJ]]
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[[Category: Dove, S.]]
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[[Category: Dove S]]
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[[Category: Hoegh-Guldberg, O.]]
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[[Category: Hoegh-Guldberg O]]
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[[Category: Ling, M.]]
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[[Category: Ling M]]
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[[Category: Oakley, A J.]]
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[[Category: Oakley AJ]]
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[[Category: Prescott, M.]]
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[[Category: Prescott M]]
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[[Category: Rossjohn, J.]]
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[[Category: Rossjohn J]]
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[[Category: Beta can fold]]
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[[Category: Blue coral pigment]]
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[[Category: Chromophore]]
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[[Category: Luminescent protein]]
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[[Category: Similar to green fluorescent protein and dsred]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 09:12:27 2009''
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Current revision

Crystal structure of Coral pigment

PDB ID 1mou

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