2e72

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{{Seed}}
 
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[[Image:2e72.png|left|200px]]
 
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==Solution structure of the zinc finger domain of human KIAA0461==
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The line below this paragraph, containing "STRUCTURE_2e72", creates the "Structure Box" on the page.
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<StructureSection load='2e72' size='340' side='right'caption='[[2e72]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2e72]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E72 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2e72| PDB=2e72 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e72 OCA], [https://pdbe.org/2e72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e72 RCSB], [https://www.ebi.ac.uk/pdbsum/2e72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e72 ProSAT], [https://www.topsan.org/Proteins/RSGI/2e72 TOPSAN]</span></td></tr>
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</table>
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===Solution structure of the zinc finger domain of human KIAA0461===
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== Function ==
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[https://www.uniprot.org/uniprot/POGZ_HUMAN POGZ_HUMAN] Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.<ref>PMID:20562864</ref>
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== References ==
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==About this Structure==
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<references/>
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2E72 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E72 OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Inoue, M.]]
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[[Category: Large Structures]]
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[[Category: Kigawa, T.]]
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[[Category: Inoue M]]
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[[Category: Muto, Y.]]
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[[Category: Kigawa T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Muto Y]]
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[[Category: Shirouzu, M.]]
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[[Category: Shirouzu M]]
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[[Category: Suzuki, S.]]
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[[Category: Suzuki S]]
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[[Category: Tanabe, W.]]
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[[Category: Tanabe W]]
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[[Category: Terada, T.]]
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[[Category: Terada T]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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[[Category: Zinc finger domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 09:32:09 2009''
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Current revision

Solution structure of the zinc finger domain of human KIAA0461

PDB ID 2e72

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