2yup

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{{Seed}}
 
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[[Image:2yup.png|left|200px]]
 
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==Solution structure of the second SH3 domain of human Vinexin==
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The line below this paragraph, containing "STRUCTURE_2yup", creates the "Structure Box" on the page.
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<StructureSection load='2yup' size='340' side='right'caption='[[2yup]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2yup]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YUP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yup OCA], [https://pdbe.org/2yup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yup RCSB], [https://www.ebi.ac.uk/pdbsum/2yup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yup ProSAT], [https://www.topsan.org/Proteins/RSGI/2yup TOPSAN]</span></td></tr>
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{{STRUCTURE_2yup| PDB=2yup | SCENE= }}
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</table>
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== Function ==
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===Solution structure of the second SH3 domain of human Vinexin===
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[https://www.uniprot.org/uniprot/VINEX_HUMAN VINEX_HUMAN] Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2YUP is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUP OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yu/2yup_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yup ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Abe, H.]]
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[[Category: Large Structures]]
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[[Category: Inoue, M.]]
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[[Category: Abe H]]
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[[Category: Kigawa, T.]]
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[[Category: Inoue M]]
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[[Category: Koshiba, S.]]
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[[Category: Kigawa T]]
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[[Category: Miyamoto, K.]]
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[[Category: Koshiba S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Miyamoto K]]
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[[Category: Saito, K.]]
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[[Category: Saito K]]
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[[Category: Sasagawa, A.]]
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[[Category: Sasagawa A]]
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[[Category: Tochio, N.]]
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[[Category: Tochio N]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama S]]
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[[Category: Cell adhesion]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Scam-1]]
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[[Category: Sh3-containing adapter molecule 1]]
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[[Category: Sorbin and sh3 domain-containing protein 3]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 10:10:33 2009''
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Current revision

Solution structure of the second SH3 domain of human Vinexin

PDB ID 2yup

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2yup"
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