1x69

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:01, 9 May 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1x69.png|left|200px]]
 
-
<!--
+
==Solution structures of the SH3 domain of human Src substrate cortactin==
-
The line below this paragraph, containing "STRUCTURE_1x69", creates the "Structure Box" on the page.
+
<StructureSection load='1x69' size='340' side='right'caption='[[1x69]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1x69]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X69 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X69 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x69 OCA], [https://pdbe.org/1x69 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x69 RCSB], [https://www.ebi.ac.uk/pdbsum/1x69 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x69 ProSAT], [https://www.topsan.org/Proteins/RSGI/1x69 TOPSAN]</span></td></tr>
-
{{STRUCTURE_1x69| PDB=1x69 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Solution structures of the SH3 domain of human Src substrate cortactin===
+
[https://www.uniprot.org/uniprot/SRC8_HUMAN SRC8_HUMAN] Contributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases.<ref>PMID:21296879</ref> <ref>PMID:16636290</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
1X69 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X69 OCA].
+
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x6/1x69_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x69 ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Inoue, M.]]
+
[[Category: Large Structures]]
-
[[Category: Kigawa, T.]]
+
[[Category: Inoue M]]
-
[[Category: Koshiba, S.]]
+
[[Category: Kigawa T]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Koshiba S]]
-
[[Category: Sato, M.]]
+
[[Category: Sato M]]
-
[[Category: Tochio, N.]]
+
[[Category: Tochio N]]
-
[[Category: Yokoyama, S.]]
+
[[Category: Yokoyama S]]
-
[[Category: Cttn]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Oncogene ems1]]
+
-
[[Category: Riken structural genomics/proteomics initiative]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Sh3 domain]]
+
-
[[Category: Signaling protein]]
+
-
[[Category: Structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 10:10:49 2009''
+

Current revision

Solution structures of the SH3 domain of human Src substrate cortactin

PDB ID 1x69

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1x69"
Personal tools