1d1m
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1d1m.png|left|200px]] | ||
- | + | ==CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT== | |
- | + | <StructureSection load='1d1m' size='340' side='right'caption='[[1d1m]], [[Resolution|resolution]] 2.05Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1d1m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D1M FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d1m OCA], [https://pdbe.org/1d1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d1m RCSB], [https://www.ebi.ac.uk/pdbsum/1d1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d1m ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance. | |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | < | + | Check<jmol> |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/1d1m_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | + | </jmolCheckbox> | |
- | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d1m ConSurf]. |
- | + | <div style="clear:both"></div> | |
- | + | __TOC__ | |
- | == | + | </StructureSection> |
- | < | + | [[Category: Escherichia virus Lambda]] |
- | [[ | + | [[Category: Large Structures]] |
- | [[ | + | [[Category: Matthews BW]] |
- | [[ | + | [[Category: Mollah AK]] |
- | [[Category: | + | [[Category: Mossing MC]] |
- | [[Category: | + | [[Category: Rupert PB]] |
- | [[Category: | + | |
- | [[Category: | + | |
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Current revision
CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT
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