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3fw9

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{{Seed}}
 
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[[Image:3fw9.jpg|left|200px]]
 
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==Structure of berberine bridge enzyme in complex with (S)-scoulerine==
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The line below this paragraph, containing "STRUCTURE_3fw9", creates the "Structure Box" on the page.
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<StructureSection load='3fw9' size='340' side='right'caption='[[3fw9]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3fw9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FW9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.489&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SLX:(13AS)-3,10-DIMETHOXY-5,8,13,13A-TETRAHYDRO-6H-ISOQUINO[3,2-A]ISOQUINOLINE-2,9-DIOL'>SLX</scene></td></tr>
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{{STRUCTURE_3fw9| PDB=3fw9 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fw9 OCA], [https://pdbe.org/3fw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fw9 RCSB], [https://www.ebi.ac.uk/pdbsum/3fw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fw9 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RETO_ESCCA RETO_ESCCA] Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fw9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fw9 ConSurf].
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<div style="clear:both"></div>
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===Structure of berberine bridge enzyme in complex with (S)-scoulerine===
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==See Also==
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*[[Reticuline oxidase|Reticuline oxidase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3FW9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FW9 OCA].
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[[Category: Eschscholzia californica]]
[[Category: Eschscholzia californica]]
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[[Category: Reticuline oxidase]]
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[[Category: Large Structures]]
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[[Category: Gruber, K.]]
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[[Category: Gruber K]]
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[[Category: Macheroux, P.]]
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[[Category: Macheroux P]]
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[[Category: Winkler, A.]]
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[[Category: Winkler A]]
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[[Category: Alakloid biosynthesis]]
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[[Category: Alkaloid metabolism]]
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[[Category: Bi-covalent flavinylation]]
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[[Category: Cytoplasmic vesicle]]
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[[Category: Fad]]
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[[Category: Flavoprotein]]
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[[Category: Glycoprotein]]
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[[Category: N-glycosylation]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 18:00:56 2009''
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Current revision

Structure of berberine bridge enzyme in complex with (S)-scoulerine

PDB ID 3fw9

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