2wiz

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[[Image:2wiz.jpg|left|200px]]
 
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==Crystal structures of Holliday junction resolvases from Archaeoglobus fulgidus bound to DNA substrate==
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The line below this paragraph, containing "STRUCTURE_2wiz", creates the "Structure Box" on the page.
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<StructureSection load='2wiz' size='340' side='right'caption='[[2wiz]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2wiz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WIZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wiz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wiz OCA], [https://pdbe.org/2wiz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wiz RCSB], [https://www.ebi.ac.uk/pdbsum/2wiz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wiz ProSAT]</span></td></tr>
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{{STRUCTURE_2wiz| PDB=2wiz | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HJC_ARCFU HJC_ARCFU] A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.[HAMAP-Rule:MF_01490]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/2wiz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wiz ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURES OF HOLLIDAY JUNCTION RESOLVASES FROM ARCHAEOGLOBUS FULGIDUS BOUND TO DNA SUBSTRATE===
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==See Also==
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*[[Resolvase 3D structures|Resolvase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2WIZ is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIZ OCA].
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[[Category: Archaeoglobus fulgidus DSM 4304]]
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[[Category: Archaeoglobus fulgidus]]
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[[Category: Large Structures]]
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[[Category: Basquin, J.]]
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[[Category: Synthetic construct]]
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[[Category: Carolis, C.]]
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[[Category: Basquin J]]
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[[Category: Koehler, C.]]
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[[Category: Carolis C]]
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[[Category: Sauter, C.]]
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[[Category: Koehler C]]
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[[Category: Suck, D.]]
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[[Category: Sauter C]]
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[[Category: Toeroe, I.]]
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[[Category: Suck D]]
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[[Category: Dna binding protein]]
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[[Category: Toeroe I]]
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[[Category: Holliday junction resolvase]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase dna complex]]
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[[Category: Hydrolase/dna complex]]
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[[Category: Type ii restriction endonuclease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 27 15:16:14 2009''
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Current revision

Crystal structures of Holliday junction resolvases from Archaeoglobus fulgidus bound to DNA substrate

PDB ID 2wiz

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