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3hfu

From Proteopedia

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{{Seed}}
 
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[[Image:3hfu.jpg|left|200px]]
 
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==Crystal structure of the ligand binding domain of E. coli CynR with its specific effector azide==
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The line below this paragraph, containing "STRUCTURE_3hfu", creates the "Structure Box" on the page.
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<StructureSection load='3hfu' size='340' side='right'caption='[[3hfu]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3hfu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HFU FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_3hfu| PDB=3hfu | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hfu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hfu OCA], [https://pdbe.org/3hfu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hfu RCSB], [https://www.ebi.ac.uk/pdbsum/3hfu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hfu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CYNR_ECOLI CYNR_ECOLI] Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR-cynTSX intergenic region.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/3hfu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hfu ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the ligand binding domain of E. coli CynR with its specific effector azide===
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3HFU is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFU OCA].
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[[Category: Escherichia coli K-12]]
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Dong, A.]]
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[[Category: Dong A]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards AM]]
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[[Category: Evdokimova, E.]]
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[[Category: Evdokimova E]]
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[[Category: Kagan, O.]]
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[[Category: Kagan O]]
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[[Category: Savchenko, A.]]
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[[Category: Savchenko A]]
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[[Category: Singer, A U.]]
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[[Category: Singer AU]]
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[[Category: Activator]]
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[[Category: Azide]]
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[[Category: Cynr]]
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[[Category: Cytoplasm]]
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[[Category: Dna-binding]]
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[[Category: Effector]]
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[[Category: Lysr transcriptional activiator]]
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[[Category: Repressor]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 18:09:51 2009''
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Current revision

Crystal structure of the ligand binding domain of E. coli CynR with its specific effector azide

PDB ID 3hfu

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