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1vkm

From Proteopedia

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(New page: 200px<br /><applet load="1vkm" size="450" color="white" frame="true" align="right" spinBox="true" caption="1vkm, resolution 1.90&Aring;" /> '''Crystal structure of...)
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[[Image:1vkm.gif|left|200px]]<br /><applet load="1vkm" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1vkm, resolution 1.90&Aring;" />
 
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'''Crystal structure of an indigoidine synthase (IndA-like) protein (TM1464) from Thermotoga maritima at 1.90 A resolution'''<br />
 
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==About this Structure==
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==Crystal structure of an indigoidine synthase a (idga)-like protein (tm1464) from thermotoga maritima msb8 at 1.90 A resolution==
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1VKM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8] with MN, UNL and EDO as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1VKM OCA].
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<StructureSection load='1vkm' size='340' side='right'caption='[[1vkm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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==Reference==
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<table><tr><td colspan='2'>[[1vkm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VKM FirstGlance]. <br>
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Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 A resolution reveals a new fold., Levin I, Miller MD, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Cambell J, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Hornsby M, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kreusch A, Kuhn P, Lesley SA, Morse A, Moy K, Nigoghossian E, Ouyang J, Page R, Quijano K, Reyes R, Robb A, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, Wang X, West B, Wolf G, Xu Q, Zagnitko O, Hodgson KO, Wooley J, Wilson IA, Proteins. 2005 Jun 1;59(4):864-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15822122 15822122]
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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[[Category: Single protein]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vkm OCA], [https://pdbe.org/1vkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vkm RCSB], [https://www.ebi.ac.uk/pdbsum/1vkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vkm ProSAT], [https://www.topsan.org/Proteins/JCSG/1vkm TOPSAN]</span></td></tr>
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[[Category: Thermotoga maritima msb8]]
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</table>
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[[Category: JCSG, Joint.Center.for.Structural.Genomics.]]
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== Function ==
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[[Category: EDO]]
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[https://www.uniprot.org/uniprot/PSUG_THEMA PSUG_THEMA] Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.<ref>PMID:18591240</ref> Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.[HAMAP-Rule:MF_01876]<ref>PMID:18591240</ref>
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[[Category: MN]]
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== Evolutionary Conservation ==
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[[Category: UNL]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: conserved hypothetical protein possibly involved in carbohydrate metabolism]]
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Check<jmol>
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[[Category: jcsg]]
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<jmolCheckbox>
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[[Category: joint center for structural genomics]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/1vkm_consurf.spt"</scriptWhenChecked>
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[[Category: protein structure initiative]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: psi]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: structural genomics]]
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</jmolCheckbox>
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[[Category: tm1464]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vkm ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 22:41:59 2007''
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermotoga maritima MSB8]]

Current revision

Crystal structure of an indigoidine synthase a (idga)-like protein (tm1464) from thermotoga maritima msb8 at 1.90 A resolution

PDB ID 1vkm

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