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2cnu

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[[Image:2cnu.gif|left|200px]]<br />
 
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<applet load="2cnu" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="2cnu, resolution 1.05&Aring;" />
 
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'''ATOMIC RESOLUTION STRUCTURE OF SAICAR-SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH ASPARTIC ACID'''<br />
 
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==About this Structure==
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==Atomic resolution structure of SAICAR-synthase from Saccharomyces cerevisiae complexed with aspartic acid==
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2CNU is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]] with SO4, ACE and ASP as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Ligase Ligase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.6 6.3.2.6]]. Structure known Active Site: AC2. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CNU OCA]].
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<StructureSection load='2cnu' size='340' side='right'caption='[[2cnu]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
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[[Category: Saccharomyces cerevisiae]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2cnu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CNU FirstGlance]. <br>
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[[Category: Antonyuk, S.V.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.05&#8491;</td></tr>
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[[Category: Barynin, V.V.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Grebenko, A.I.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cnu OCA], [https://pdbe.org/2cnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cnu RCSB], [https://www.ebi.ac.uk/pdbsum/2cnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cnu ProSAT]</span></td></tr>
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[[Category: Lamzin, V.S.]]
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</table>
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[[Category: Levdikov, V.M.]]
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== Function ==
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[[Category: Melik-Adamyan, W.R.]]
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[https://www.uniprot.org/uniprot/PUR7_YEAST PUR7_YEAST]
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[[Category: Popov, A.N.]]
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== Evolutionary Conservation ==
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[[Category: Urusova, D.V.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: ACE]]
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Check<jmol>
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[[Category: ASP]]
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<jmolCheckbox>
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[[Category: SO4]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/2cnu_consurf.spt"</scriptWhenChecked>
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[[Category: acetylation]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: atpbinding protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: phosphoribosylaminoimidazolesuccinocarboxamide (saicar) syn ligase]]
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</jmolCheckbox>
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[[Category: purine biosynthesis]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cnu ConSurf].
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[[Category: synthetase]]
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:25:17 2007''
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==See Also==
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*[[SAICAR synthetase|SAICAR synthetase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Antonyuk SV]]
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[[Category: Barynin VV]]
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[[Category: Grebenko AI]]
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[[Category: Lamzin VS]]
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[[Category: Levdikov VM]]
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[[Category: Melik-Adamyan WR]]
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[[Category: Popov AN]]
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[[Category: Urusova DV]]

Current revision

Atomic resolution structure of SAICAR-synthase from Saccharomyces cerevisiae complexed with aspartic acid

PDB ID 2cnu

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