2kjy
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2kjy is ON HOLD Authors: Mori, S., Iwaoka, R., Eto, M., Ohki, S. Description: MYPT1(658-714) ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ]...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==MYPT1(658-714)== | |
| - | + | <StructureSection load='2kjy' size='340' side='right'caption='[[2kjy]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2kjy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kjy OCA], [https://pdbe.org/2kjy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kjy RCSB], [https://www.ebi.ac.uk/pdbsum/2kjy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kjy ProSAT]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MYPT1_HUMAN MYPT1_HUMAN] Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.<ref>PMID:19245366</ref> <ref>PMID:18477460</ref> <ref>PMID:20354225</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kjy_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kjy ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Eto M]] | ||
| + | [[Category: Iwaoka R]] | ||
| + | [[Category: Mori S]] | ||
| + | [[Category: Ohki S]] | ||
Current revision
MYPT1(658-714)
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Categories: Homo sapiens | Large Structures | Eto M | Iwaoka R | Mori S | Ohki S
