We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

1nay

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="1nay" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nay, resolution 2.60&Aring;" /> '''GPP-Foldon:X-ray str...)
Current revision (13:27, 13 March 2024) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1nay.gif|left|200px]]<br /><applet load="1nay" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1nay, resolution 2.60&Aring;" />
 
-
'''GPP-Foldon:X-ray structure'''<br />
 
-
==Overview==
+
==GPP-Foldon:X-ray structure==
-
In a designed fusion protein the trimeric domain foldon from bacteriophage, T4 fibritin was connected to the C terminus of the collagen model peptide, (GlyProPro)(10) by a short Gly-Ser linker to facilitate formation of the, three-stranded collagen triple helix. Crystal structure analysis at 2.6 A, resolution revealed conformational changes within the interface of both, domains compared with the structure of the isolated molecules. A striking, feature is an angle of 62.5 degrees between the symmetry axis of the, foldon trimer and the axis of the triple helix. The melting temperature of, (GlyProPro)(10) in the designed fusion protein (GlyProPro)(10)foldon is, higher than that of isolated (GlyProPro)(10,) which suggests an entropic, stabilization compensating for the destabilization at the interface.
+
<StructureSection load='1nay' size='340' side='right'caption='[[1nay]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[1nay]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NAY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NAY FirstGlance]. <br>
-
1NAY is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NAY OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nay FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nay OCA], [https://pdbe.org/1nay PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nay RCSB], [https://www.ebi.ac.uk/pdbsum/1nay PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nay ProSAT]</span></td></tr>
-
==Reference==
+
</table>
-
Collagen stabilization at atomic level: crystal structure of designed (GlyProPro)10foldon., Stetefeld J, Frank S, Jenny M, Schulthess T, Kammerer RA, Boudko S, Landwehr R, Okuyama K, Engel J, Structure. 2003 Mar;11(3):339-46. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12623021 12623021]
+
== Evolutionary Conservation ==
-
[[Category: Protein complex]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Stetefeld, J.]]
+
Check<jmol>
-
[[Category: collagen assembly]]
+
<jmolCheckbox>
-
 
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/1nay_consurf.spt"</scriptWhenChecked>
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 22:51:55 2007''
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nay ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Escherichia coli]]
 +
[[Category: Large Structures]]
 +
[[Category: Stetefeld J]]

Current revision

GPP-Foldon:X-ray structure

PDB ID 1nay

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1nay"
Personal tools