1jce

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(New page: 200px<br /><applet load="1jce" size="450" color="white" frame="true" align="right" spinBox="true" caption="1jce, resolution 2.1&Aring;" /> '''MREB FROM THERMOTOGA ...)
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[[Image:1jce.gif|left|200px]]<br /><applet load="1jce" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1jce, resolution 2.1&Aring;" />
 
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'''MREB FROM THERMOTOGA MARITIMA'''<br />
 
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==Overview==
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==MREB FROM THERMOTOGA MARITIMA==
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It was thought until recently that bacteria lack the actin or tubulin, filament networks that organize eukaryotic cytoplasm. However, we show, here that the bacterial MreB protein assembles into filaments with a, subunit repeat similar to that of F-actin-the physiological polymer of, eukaryotic actin. By elucidating the MreB crystal structure we demonstrate, that MreB and actin are very similar in three dimensions. Moreover, the, crystals contain protofilaments, allowing visualization of actin-like, strands at atomic resolution. The structure of the MreB protofilament is, in remarkably good agreement with the model for F-actin, showing that the, proteins assemble in identical orientations. The actin-like properties of, MreB explain the finding that MreB forms large fibrous spirals under the, cell membrane of rod-shaped cells, where they are involved in cell-shape, determination. Thus, prokaryotes are now known to possess homologues both, of tubulin, namely FtsZ, and of actin.
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<StructureSection load='1jce' size='340' side='right'caption='[[1jce]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1jce]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JCE FirstGlance]. <br>
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1JCE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JCE OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jce OCA], [https://pdbe.org/1jce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jce RCSB], [https://www.ebi.ac.uk/pdbsum/1jce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jce ProSAT]</span></td></tr>
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Prokaryotic origin of the actin cytoskeleton., van den Ent F, Amos LA, Lowe J, Nature. 2001 Sep 6;413(6851):39-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11544518 11544518]
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</table>
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[[Category: Single protein]]
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== Function ==
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[https://www.uniprot.org/uniprot/Q9WZ57_THEMA Q9WZ57_THEMA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jc/1jce_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jce ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Amos, L.A.]]
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[[Category: Amos LA]]
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[[Category: Ent, F.van.den.]]
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[[Category: Lowe J]]
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[[Category: Lowe, J.]]
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[[Category: Van den Ent F]]
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[[Category: actin]]
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[[Category: ftsz]]
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[[Category: hsp-70]]
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[[Category: mbl]]
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[[Category: mreb]]
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[[Category: rod-shape determining]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 23:27:09 2007''
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Current revision

MREB FROM THERMOTOGA MARITIMA

PDB ID 1jce

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